Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst [mouse_ERKi_scRNAseq]

An immunological mechanism of resistance to CDK4/6 inhibitors in breast cancer

Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity [Mouse_CD45_scRNA]

Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging [snATAC-Seq] [10X Multiome]

Il7rKO Single Cell

Defining molecular circuits of CD8+ T cell responses in tissues during latent viral infection

AireDTR Single Cell

Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration

Single Cell Map of RORgt Lineage APCs in Early Life

Autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells

Orexin/Hypocretin Receptor 2 Signaling in MCH Neurons Regulates REM sleep and Insulin Sensitivity

Mapping the Evolution of Acinar cell derived Pancreatic Preneoplastic Lesions in a Mouse Model: A Detailed Transcriptomic and Pathological Characterization

Tissue-resident memory CD8 T Cell Diversity is Spatiotemporally Imprinted [snRNA-Seq]

Single cell RNA sequencing of TCF-1+ precursor cells reacting to LCMV gp33 vs np396 multimers sorted 30 days after infection with LCMV Armstrong [scRNA-Seq + TCR 10x]

Epitope tagging with genome editing in mice reveals that the proton channel OTOP1 is apically localized and not restricted to Type III “sour” taste receptor cells

Neutrophils physically interact with tumor cells to form a signaling niche promoting breast cancer aggressiveness

Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation [scMultiomics]

Fate plasticity of interneuron specification

Dynamic behavior and lineage plasticity of the pulmonary venous endothelium

Progesterone signaling in oviductal epithelial cells modulates the immune response to support preimplantation embryonic development