Enhanced detection of RNA modifications with high-accuracy nanopore RNA basecalling models

High-throughput splicing assays identify missense and silent splice-disruptive POU1F1 variants underlying pituitary hormone deficiency

Position-dependent function of human sequence-specific transcription factors

The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation [MPRA]

The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation

Joint epigenome profiling reveals cell-type-specific gene regulatory programs in human cortical organoids

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming

YBX1 HITS-CLIP

Production of functional small interfering RNAs by human Dicer

Rocaglamide A converts RNA helicase eIF4A into a sequence-specific translational repressor

Genome-wide identification of snoRNA-guided 2?-O-methylation sites with CLIP and Ribometh-seq

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor

Selective stalling of human translation through small molecule engagement of the ribosome nascent chain

In vivo delivery of CRISPR/Cas9 nanocomplexes in post-mitotic neurons for Alzheimer’s disease therapy

Discovery of IL2RA and CD69 enhancers using CRISPRa

Bacterial artificial chromosomes establish replication timing and sub-nuclear compartment de novo as extra-chromosomal vectors [repli-seq]

Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [DNA-seq]

Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks

BART-Seq: cost-effective massively parallelized targeted sequencing for genomics, transcriptomics, and single-cell analysis