A Lactate-induced SREBF2-dependent genetic program drives an immunotolerant dendritic cell population during cancer progression

A genetic-metabolic axis for metastatic liver organotropism

A single cell atlas of human glioma under therapy

Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis.

An activity-specificity trade-off encoded in human transcription factors

An in situ method for identification of transcriptome-wide protein-RNA interactions in cells

An in situ method for identification of transcriptome-wide protein-RNA interactions in cells [in_situ_STAMP]

Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by single-cell transcriptomics

BAP1 activity regulates Polycomb occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition

ChromaFold predicts the 3D contact map from single-cell chromatin accessibility

Concurrent profiling of multiscale 3D genome organization and gene expression in single mammalian cells

DNA methyltransferase 1 modulates mitochondrial function through bridging m5C RNA methylation

Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics

Decoding the immune checkpoint signatures in human atherosclerosis: implications of type 2 diabetes and lipid-lowering intervention

Dissecting developmental disorders caused by CTCF mutation at R567

Dual nuclease single-cell lineage tracing by Cas9 and Cas12a

ETV6 Represses Inflammatory Response Genes and Regulates HSPC Function During Stress Hematopoiesis in Mice

Enhancer grammar of liver cell types and hepatocyte zonation states

Epithelial-Immune Metabolic Codependency Fuels Inflammatory Disease

Genome editing by dual nucleases records deep lineage hierarchy with high fidelity.