A Quantitative Sequencing Method for 5-Formylcytosine in RNA

A genetic-metabolic axis for metastatic liver organotropism

A single-cell method to map higher-order 3D genome organization in thousands of individual cells reveals structural heterogeneity in mouse ES cells

Aberrant translation regulation by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives HNSCC progression

Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease

BAP1 activity regulates Polycomb occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes [Hi-C]

Complex Genomic Patterns of Abasic Sites in Mammalian DNA Revealed by High-Resolution SSiNGLe-AP Method

Defining genome architecture at base-pair resolution

Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution

Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform

Genome-wide determinants of Tn5 insertion preference

HOTTIP reinforces CTCF-defined TAD boundaries by forming R-loops to drive Wnt/b-catenin target gene expression in AML leukemogenesis

HOXBLINC is aberrantly expressed in acute myeloid leukemia and functions as a potent oncogenic long non-coding RNA in leukemogenesis

Hi-TrAC reveals fine-scale chromatin structures organized by transcription factors

High Resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells

High-content single-cell combinatorial indexing

Identification of Pathogenic Immune Cell Subsets in Checkpoint Inhibitor-induced Myocarditis

In vivo adenine base editing of PCSK9 in mice and macaques reduces LDL-cholesterol levels [RNA-seq]

Joint epigenome profiling reveals cell-type-specific gene regulatory programs in human cortical organoids