Improved split prime editors enable efficient in vivo genome editing.

Clinically translatable mitochondrial gene therapy in muscle using tandem zinc finger nuclease architecture

PTP inhibition improves the macrophage anti-tumor immune response and the efficacy of chemo- and radiotherapy [GeoMX profiling]

Pro-inflammatory Pathways Contribute to Pathogenesis of Clostridioides difficile Infection in a Murine Model - A Spatial Transcriptomics Study

Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2

Dysregulated ac4C modification of mRNA in a mouse model of early stage Alzheimer's disease.

Spatial transcriptomics: P. aeruginosa corneal infection

Heterozygous GAA knockout is nonconsequential on metabolism and the spatial liver transcriptome in high-fat diet induced obese and prediabetic mice

Methyltransferase-like 3 mediates m6A modification of heme oxygenase 1 mRNA to induce ferroptosis of renal tubular epithelial cells in acute kidney injury

m6A sequences 2 WT_input vs 2 Ythdf1 KO_input

Dysregulated ac4C modification of mRNA in a mouse model of early stage Alzheimer's disease [acRIP-seq]

Identification of antigen-presenting cell-T cell interactions driving immune responses to food

Licochalcone B alleviates Crohn’s Disease injury by targeting FTO [meRIP-seq]

PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation

ACBP/DBI protein neutralization for the experimental treatment of fatty liver disease

Foxa1-Mediated Chromatin Remodeling and Enhancer Reprogramming Promotes Gemcitabine Resistance in Pancreatic Cancer

NK cell cytotoxicity shapes the clonal evolution of B cell leukemia [DNA barcoding]

scRNA-seq of spleen cells from mice immunized with AALI or LNP for monkeypox vaccine development

The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA

Improvement of MASLD and MASH by suppression of hepatic N-Acetyltransferase 10 (RIP-Seq)