10X single-cell RNA-seq profiling of T cells from the pancreas, pancreatic lymph nodes, and blood of NOD mice with spontaneous or anti-PD-1-induced Type 1 Diabetes

3′ sequencing from human Huntington's disease and control motor cortex and cerebellum.

3D genome structures of single differentiating mouse ES cells reveal a unique reorganisation of chromatin in the formative state

3D structures of individual mammalian genomes reveal principles of nuclear organization

9sCa: MSL2 is an allelic dosage sensor in mammals

A Central Role for PRC1 in Shaping the 3D Nuclear Landscape

A Lactate-induced SREBF2-dependent genetic program drives an immunotolerant dendritic cell population during cancer progression

A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

A SOX2 engineered epigenetic silencer factor represses the glioblastoma genetic program

A Transcriptional Switch Governs Fibroblast Activation in Heart Disease

A cellular hierarchy in melanoma uncouples growth and metastasis

A critical requirement for IκBα in controlling dormancy in Hematopoietic stem cells via retinoic acid during embryonic development

A genetic-metabolic axis for metastatic liver organotropism

A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance

A human tissue screen identifies a regulator of ER secretion as a brain size determinant

A human tissue screen identifies a regulator of ER secretion as a brain size determinant [organoid - lineage tracing]

A ketogenic diet can revert acquired resistance to immunotherapy in prostate cancer through β-hydroxybutyrate-mediated inhibition of histone deacetylases

A lymphatic-stem cell interactome regulates intestinal stem cell activity

A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma.