Cholinergic regulation of thymocyte negative selection

IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells

Gut-Lung Microbiota Dynamics in Mice Exposed to Nanoplastics

Expansion of in vivo HDAd-transduced HSPCs by constitutive expression of tHMGA2 without additional treatment allows for therapeutically relevant transgene expression in HSPC progeny cells without clonal dominance.

Identification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance

SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

DSS-colitis induced in young age accelerates the onset of cognitive defects in Tg2576 mice, a model of Alzheimer disease

Responders to immune checkpoint therapy display early clonal expansion of tumour-infiltrating lymphocytes

Innate-like T cell subset commitment in the murine thymus is independent of TCR characteristics and occurs during proliferation

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF

Experimental tests strongly challenge the evidence of a healthy human blood microbiome

A ketogenic diet can revert acquired resistance to immunotherapy in prostate cancer through β-hydroxybutyrate-mediated inhibition of histone deacetylases

Evaluating the microbiota shift caused by Msc knock-out in wild type and DSS-induced colitis mice

Composition of colonic microbes in mice deficient in intestinal Treg subsets

A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells

Large-scale analysis of the integration of enhancer-enhancer signals by promoters

Molecular characterization stratifies VQ myeloma cells into two clusters with distinct risk signatures and drug responses [Repertoire-Seq]

Molecular characterization stratifies VQ myeloma cells into two clusters with distinct risk signatures and drug responses

A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages

Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity