Cranial radiotherapy profoundly affects glia without inducing widespread cellular senescence

LINE-1 transposable elements regulate the exit of human pluripotency and early brain development

Spatial Proteomics and Transcriptomics Reveal Early Immune Cell Organization in Pancreatic Intraepithelial Neoplasia

Mapping and engineering RNA-driven architecture of the multiphase nucleolus

Virus-Human Chromatin Interactions Reorganise 3D Genome and Hijack KDM5B for Promoting Metastasis in Nasopharyngeal Carcinoma [10X Visum Spatial Transcriptome]

Cathepsin L-Dependent Positive Selection Shapes Clonal Composition and Functional Fitness of CD4 T Cells [TCR]

Rewired type I IFN signaling is linked to age-dependent differences in COVID-19

A Stat1 gain-of-function mutant disrupts normal Stat4 innate lymphocyte programs during viral infection [scMulti-omics-seq]

Spatial component of: CELSR3 deficiency leads to tic-related behaviors and dopaminergic alterations in the striatum

Divergent Evolution of Malignant Subclones: A Balance Between Induced Aggressiveness and Intrinsic Drug Resistance in cutaneous T-cell lymphoma

A20’s Linear Ubiquitin Binding Motif Restrains Pathogenic Activation of TH17/22 cells and IL-22 Driven Enteritis [scRNA-seq]

Clonal CD8 T cells orchestrate arrhythmogenic inflammation in immune checkpoint inhibitor-associated myocarditis

Clonal CD8 T cells orchestrate arrhythmogenic inflammation in immune checkpoint inhibitor-associated myocarditis

Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration

Epigenetic and 3D genome reprogramming during the aging of human hippocampus

Spatial transcriptomics unveils novel potential disease mechanisms associated with the microenvironment in Multiple Myeloma

The Tumor-Sentinel Lymph Node Immune Migratome Reveals a Key Role for Migratory CCR7+ Dendritic Cells in Response to Immunoradiotherapy [CITE-seq]

Vaccine Educated T cells and a CD123 Bi-Specific T-Cell Engager for Treatment of Acute Myeloid Leukemia

High-coverage allele-resolved single-cell DNA methylation profiling by scDEEP-mC reveals cell lineage, X-inactivation state, and replication dynamics

Scalable generation and functional classification of genetic variants in inborn errors of immunity to accelerate clinical diagnosis and treatment