Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice

Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals

Spatial Mapping of Mouse Brain Aging through Indexed Sequencing

scRNA-seq, snATAC-seq, and spatial transcriptomics analysis of mammary glands of aged female mice

A novel model of binge ethanol exposure reveals enhanced neurodegeneration with advanced age

Microglia-mediated T cell Infiltration Drives Neurodegeneration in Tauopathy

germ cells

Monoclonal Antibody Blockade of CD226 Decreases Spontaneous Diabetes in the NDO Mouse by Augmenting Treg and Diminishing Effector Functionality

In vivo single-cell CRISPR uncovers distinct TNF-α programs in tumor evolution

Single-cell analysis of Tgfbr2-KO pulmonary monocytes and interstitial macrophages

Myeloid cell-based delivery of IFN-γ reprograms leukemia microenvironment and induces anti-tumoral immune responses

Gene expression of single cell of rhabdomyolysis induced acute kidney injury cells

Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens

In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases [Visium]

In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases

Spatiotemporal hepatocyte heterogeneity impacts in vivo gene engineering [Visium Spatial Transcriptomics]

Spatiotemporal hepatocyte heterogeneity impacts in vivo gene engineering

Recruitment of stem-like T cells and resistance to exhaustion support CD4 T cell responses in autoimmunity (scCITE-Seq).

A critical requirement for IκBα in controlling dormancy in Hematopoietic stem cells via retinoic acid during embryonic development

Amyloid driven clonally expanded CD8+ effector memory T cells infiltrate Alzheimer’s disease bigenic mouse models