Non-Invasive Detection of Allele-Specific CRISPR-SaCas9-KKH Disruption of TOR1A DYT1 Allele in A Xenograft Mouse Model

Efficient and multiplexed somatic genome editing with Cas12a mice

Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation [CLIP]

The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis.

Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening

Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2

Long range regulation of transcription scales with genomic distance in a gene specific manner

CRISPR-SaCas9-KKH targeting of miR-21 through a single adeno-associated virus vector prolongs survival of GB-bearing mice

Identification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance

The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene [Tagmentation]

ITPK1 sensitizes tumor cells to IgA-dependent neutrophil killing in vivo

ITPK1 sensitizes tumor cells to IgA-dependent neutrophil killing in vivo [CRISPR Epistasis]

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER [CRISPR]

In vivo CRISPR base editing for treatment of Huntington’s disease

Gut Dysbiosis Impacts Brain Metastasis Outgrowth and Immune Response Dynamics

Expansion of in vivo HDAd-transduced HSPCs by constitutive expression of tHMGA2 without additional treatment allows for therapeutically relevant transgene expression in HSPC progeny cells without clonal dominance.

Gut-Lung Microbiota Dynamics in Mice Exposed to Nanoplastics

Apobec-Mediated Retroviral Hypermutation In Vivo is Dependent on Mouse Strain