WNT signaling in human pluripotent stem cells promotes HDAC2-dependent epigenetic programs and development of retinoic acid-responsive mesoderm

LINE-1 transposable elements regulate the exit of human pluripotency and early brain development

Single-nuclei multiome (ATAC + Gene Expression) sequencing of CD40L-activated human plasmacytoid dendritic cells

Single-nuclei multiome (ATAC + Gene Expression) sequencing of purified human dendritic cells

Single-nuclei multiome (ATAC + Gene Expression) sequencing of human plasmacytoid dendritic cells

Aberrant TNF signaling in pancreatic lymph nodes of patients with Type 1 Diabetes

Defining the landscape of chromatin-associated RNAs at human centromeric repeats

Investigate FOXA2 driven lineage plasticity in prostate cancer cells by single-cell Multiome ATAC + Gene Expression assay.

Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer

Neutrophils recruited by NKX2-1 suppression via activation of CXCLs/CXCR2 axis promote lung adenocarcinoma progression

Joint representation and visualization of derailed cell states with Decipher [scATAC-seq]

Enhanced gliogenesis and delayed maturation underpin the neurodevelopmental defects in Lowe syndrome

Chemical-based external stimulation reprograms BJs into FiNs (scATAC-seq)

Chemical-based external stimulation reprograms BJs into FiNs

The histone acetyltransferase MOZ is a molecular dependency and therapeutic target in NUP98-rearranged acute myeloid leukemia [WGS, ATACseq, CUT&RUN, scRNAseq]

Gastric niche in the regulation of the epithelial cell differentiation in the human and mouse

Gene regulatory programs of NK cells show that NCAM1 (CD56) and KIRs are controlled by genetically polymorphic distal regulatory elements [scATAC-seq]

Epigenetic remodeling via HDAC6 inhibition amplifies anti-tumoral immune responses in pediatric AML [ATAC-seq]

Patterns of intra- and inter-tumor phenotypic heterogeneity in men with lethal prostate cancer [scATAC-seq]

Patterns of intra- and inter-tumor phenotypic heterogeneity in men with lethal prostate cancer