Antiandrogen treatment endows ZMYDN8 dependent epigenetic reprogramming to orchestrate neuroendocrine tumor transdifferentiation

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.

ISWI chromatin remodeler SMARCA5 is essential for meiotic gene expression and male fertility in mammals

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Yin Yang 1 Deficiency in Skeletal Muscle Stem Cell Aggravates Muscle Fibrosis in Duchenne Muscular Dystrophy Mouse by Disrupting Muscle Stem Cell/Macrophage/Fibro-adipogenic Progenitor Crosstalk

Adipose tissue retains an epigenetic memory of obesity after weight loss

Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C

Decoding Aging in the Heart via Single Cell Dual Omics of Non-Cardiomyocytes (scATAC-Seq)

Decoding Aging in the Heart via Single Cell Dual Omics of Non-Cardiomyocytes

H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium

CPSF6-RARγ Interacts with HDAC3 to Promote Myeloid Transformation

Stem Cell Activity-Coupled Suppression of Endogenous Retrovirus Governs Adult Tissue Regeneration

Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer

Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy.

Transcriptomic analysis of cell-of-origin CNS neuroblastoma, FOXR2 activated [Multiome]

Liver-specific matrin-3 knockout regulates hepatic transcriptome and chromatin accessibility in mice

The Functional Roles of HDAC1 and HDAC2 in Neurodevelopment of the Mouse Brain

Single-nucleus Multiome ATAC and Gene Expression analysis of the liver tissues from matrin-3 floxed and liver-specific knockout mice

scRNA-seq, snATAC-seq, and spatial transcriptomics analysis of mammary glands of aged female mice

Potential landscape decomposes the cell identity conversion in liver regeneration and tumorigenesis