Tumor-Infiltrating CTL expansion and effector functions depends on Slc7a5-dependent tryptophan update

Metastatic site influences driver gene function in pancreatic cancer [scMultiome]

Metastatic site influences driver gene function in pancreatic cancer

Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging [snATAC-Seq] [10X Multiome]

Monocytes can efficiently replace all brain macrophages and instruct different microglial identities depending on their origin

Spatial organization, chromatin accessibility and gene-regulatory programs defining sensory neurons

Integrative Single-Cell RNA and ATAC Sequencing Reveals the Impact of Chronic Cigarette Smoking on Lung Epithelial Responses to Influenza and Hyperoxia

Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen [scATAC-Seq]

Epidermal loss of PRMT5 leads to the emergence of an atypical basal keratinocyte-like cell population and defective skin stratification [multiome]

Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate [coassay_TOXKO]

Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate [coassay_TOXKO_LCMV_Arm_rechalle]

KMT2C Deficiency Drives Luminal Transdifferentiation into Double-Negative Prostate Cancer and Sensitizes to Fatty Acid Synthase Inhibition [scRNA-Seq]

scATAC-seq of antigen-specific CD8+ T cells from different time-course of LCMV-Armstrong infected mice

Chromatin landscape alteration uncovers multiple transcriptional circuits during memory CD8+ T cell differentiation

scATAC-seq of OT-1 CD8+ T cells from different time-course of Lm-OVA infected mice

Myeloid C3 causes neuronal injury prior to synapse loss [snMulti-ome-seq]

Myeloid C3 causes neuronal injury prior to synapse loss

TET2 Deficiency Increases the Competitive Advantage of Hematopoietic Stem Cells through Upregulation of Thrombopoietin Receptor Signaling

Heparan sulfate regulates myofibroblast heterogeneity and function to mediate niche homeostasis during alveolar morphogenesis

Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution