Single-cell transcriptome conservation in a multispecies comparative analysis of fresh and cryopreserved insulinoma cell lines

Two microbiome metabolites compete for tRNA modification and mammalian cell proliferation

The histone acetyltransferase MOZ is a molecular dependency and therapeutic target in NUP98-rearranged acute myeloid leukemia [WGS, ATACseq, CUT&RUN, scRNAseq]

Gastric niche in the regulation of the epithelial cell differentiation in the human and mouse

DNA methyltransferase 1 modulates mitochondrial function through bridging m5C RNA methylation

Transcriptional and functional architecture of the whole neutrophil compartment

The Inflammaging Microenvironment Induces Dysfunctional Rewiring of Tfh Cell Differentiation

STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation

Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity

Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by single-cell transcriptomics [snRNA-seq]

Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by single-cell transcriptomics

Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets

Selective inhibition of matrix mechanosensing in stromal cells attenuates cardiovascular fibrosis

Heterogeneous Cardiac- and Neural Crest-Derived Aortic Smooth Muscle Cells have Similar Transcriptional Changes after TGFβ Signaling Disruption

Targeting Senescent Hepatocytes for Treatment of Metabolic Dysfunction-associated Steatotic Liver Disease and Multi-organ Dysfunction

POISONING OF HEALTHY HEMATOPOIESIS IS AN UNANTICIPATED MECHANISM DRIVING CLONAL DOMINANCE IN VEXAS SYNDROME [scRNA-seq]

HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98 fusion transformed leukemia

G-Quadruplex DNA Suppresses Transcriptional Pause Release During DNA Replication

Inhibiting CXCR4 Attenuates TOX-Programmed Exhausted Phenotype of CD8+ T cells via Regulating JAK2/STAT3 Pathway

A unified molecular approach for spatial epigenome, transcriptome, and cell lineages