Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity

Selective inhibition of matrix mechanosensing in stromal cells attenuates cardiovascular fibrosis

Targeting Senescent Hepatocytes for Treatment of Metabolic Dysfunction-associated Steatotic Liver Disease and Multi-organ Dysfunction

Intrapulmonary metastases of non-small cell lung cancer promoted by a hotspot gain-of-function mutation in KMT2C

G-Quadruplex DNA Suppresses Transcriptional Pause Release During DNA Replication

The Inflammaging Microenvironment Induces Dysfunctional Rewiring of Tfh Cell Differentiation

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.

STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation

Differential KEAP1/NRF2-mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy

A unified molecular approach for spatial epigenome, transcriptome, and cell lineages

Differential KEAP1/NRF2-mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy [seq]

NK cell cytotoxicity shapes the clonal evolution of B cell leukemia [RNA-seq]

Mapping snoRNA-target RNA interactions in an RNA binding protein-dependent manner with chimeric eCLIP [chimeric eCLIP]

Identification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance

Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy

Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development [scRNAseq and scATACseq]

Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development

Evolution of myeloid-mediated immunotherapy resistance in prostate cancer

IgE plasma cells differentially regulate antibody secretion, ER stress and tissue-specific longevity relative to other isotypes

Germline TET2 variants contribute to the pathogenesis of kidney disease through impaired DNA damage repair and the activation of cytosolic nucleotide sensors