Non-Invasive Detection of Allele-Specific CRISPR-SaCas9-KKH Disruption of TOR1A DYT1 Allele in A Xenograft Mouse Model

Development of a potent epigenetic editor targeting human PCSK9 with durable reduction of cholesterol in mice and non-human primates [hybrid capture methylseq]

Development of a potent epigenetic editor targeting human PCSK9 with durable reduction of cholesterol in mice and non-human primates

Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER [CRISPR]

Identification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance

Chromatin Conformation Dynamics are essential to Control the Transcription of INK4/ARF locus

In vivo CRISPR base editing for treatment of Huntington’s disease

High-resolution transcriptional analysis of immunoglobulin variable regions reveals the absence of direct relationships between somatic hypermutation, nascent transcription and epigenetic marks [MutPE]

High-resolution transcriptional analysis of immunoglobulin variable regions reveals the absence of direct relationships between somatic hypermutation, nascent transcription and epigenetic marks

Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq

Development of a ß-Globin Gene Replacement Strategy as a Therapeutic Approach for ß-Hemoglobinopathies

SPLICER: A Highly Efficient Base Editing Toolbox That Enables in vivo Exon Skipping For Targeting Alzheimer’s Disease [miSeq]

SPLICER: A Highly Efficient Base Editing Toolbox That Enables in vivo Exon Skipping For Targeting Alzheimer’s Disease

Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations

Base editor induced mutation spectrum in GFP, human ATP1a1, human TP53BP1 and murine MyoD

TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions.

TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions

Amino acid availability is a crucial factor for survivability of cancer cells

Targeting Duchenne Muscular Dystrophy by Skipping DMD Exon 45 with Base Editors