MGA directly recruits SETDB1/ATF7IP for histone H3K9me3 on meiosis-related genes in mouse embryonic stem cells.

Modularity of OCT4 underlies its functional diversity in reprogramming and embryonic development (mES ATAC-seq)

The histone H3 lysine 36 demethylase KDM2A/FBXL11 is essential for germ cell development in male mice [ChIP-Seq]

PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation

The histone H3 lysine 36 demethylase KDM2A/FBXL11 is essential for germ cell development in male mice

Opposing lineage specifiers induce a pro-tumor hybrid-identity state in lung adenocarcinoma [ChIP-seq]

BAHCC1 promotes gene expression in neuronal cells by antagonizing SIN3A-HDAC1

Hyper transcription underlines de novo establishment of 3D chromatin architecture in mouse early embryos

IT-scC&T-seq streamlines scalable, parallel profiling of protein-DNA interactions in single cells

MYC couples SWI/SNF and metabolic reprogramming to sustain minimal residual disease in mTORC1-activated cancer cells [CUT&RUN, ATAC-seq]

MYC couples SWI/SNF and metabolic reprogramming to sustain minimal residual disease in mTORC1-activated cancer cells

EGR2 O-GlcNAcylation Orchestrates the Development of Protumoral Macrophages to Limit CD8+ T Cell Antitumor Responses.

The transcription factor IRF4 regulates the differentiation and function of intestinal ILC3s

Cohesin recruitment to promoters and enhancers by general transcription factors and chromatin regulators

Oridonin as a Novel KDM5C Inhibitor Alleviates Clonal Hematopoiesis Induced Cardiac Aging via H3K4me3 Dependent SASP Suppression [ChIP-seq]

Eradicating neuroblastomas by an RBM39 degrader in combination with anti-GD2 immunotherapy regardless of cancer cell state alterations

Distinct BMP-Smad Signaling Outputs Confer Diverse Functions in Dental Mesenchyme [CUT&Run]

Distinct BMP-Smad Signaling Outputs Confer Diverse Functions in Dental Mesenchyme [RNA-seq]

NOTCH1 reverses innate immune suppression in small cell lung cancer.

Alterations in Bile Acid Physiology in Wilson Disease [ChIP-seq]