Orchestrating endothelial cell fate regulation and function during multiple organs’ development, stress and aging at single cell resolution

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

Optimized methods for mapping DNA double-strand-break ends and resection tracts and application to meiotic recombination in mouse spermatocytes

In vivo self-assembly and targeted delivery of EGFR siRNA-encapsulating small extracellular vesicles to EGFR-positive cancer cells for NSCLC therapy

Functional Interaction between APOE4 and mutant APP promotes cerebrovascular changes in young animals

CREB-Regulated Transcription During Glycogen Synthesis in Astrocytes

Comparison of transcriptomic profiles between HFPO-DA and positive controls for PPARa, PPARg or cytotoxicity in mouse, rat, and pooled human hepatocytes

Transcriptome changes in Olig2-3 over-expression retina ganglion cells (RGCs) by AAV-Olig1/2.

Obesity Disrupts the Pituitary-Hepatic UPR Communication Leading to NAFLD Progression (liver bulk RNA seq)

Obesity Disrupts the Pituitary-Hepatic UPR Communication Leading to NAFLD Progression (pituitary bulk RNA seq)

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity [mouse_vivo_tet2_rnaseq]

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity (mouse_vivo_cgas_RT_rnaseq)

Effect of depletion of the serine protease inhibitors (serpina3n) on gene expression in cardiac fibroblasts after myocardial injury (MI) in rodent models

Obesity Disrupts the Pituitary-Hepatic UPR Communication Leading to NAFLD Progression (pituitary scRNA seq)

Single-nucleus transcriptomic sequencing and cross integration comparison of multiple species revealed new cell composition and specific gene marker in hippocampal aging

EGFR pathway regulates the cellular interactome within the liver fibrotic niche

Embryonic myeloid cells orchestrate niche cell homeostasis critical for the establishment of the definitive HSC pool

Acute social isolation alters synaptic plasticity in lateral habenula and social decision

Differential transcriptome analysis of naïve T cell activtion, TH1 cell differentiation and TH1 cell reactivation

Sepsis-secreted G6PD supports guanine generation and Histone H3K27 demethylation to drive inflammatory macrophages