The interplay between prior selection, mild intermittent exposure, and acute severe exposure in phenotypic and transcriptional response to hypoxia

Single-cell multi-omics in human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.

Chromosome silencing in vitro reveals trisomy 21 causes cell-autonomous deficits in angiogenesis and early dysregulation in Notch signaling

G+C content of transcribed sequence modulates DSIF-assisted DNA occupancy by RNA polymerase II [ChIP-seq]

G+C content of transcribed sequence modulates DSIF-assisted DNA occupancy by RNA polymerase II [RNA-seq]

APRIL drives a co-ordinated but diverse response as a foundation for plasma cell longevity [I]

A single cell atlas of human glioma under therapy

Distinctive properties of endothelial cells from tumor and normal tissue in human breast cancer

RNA sequencing of Normal Human Fibroblasts and Patient Fibroblasts with Novel SCP2 Variant

APRIL drives a co-ordinated but diverse response as a foundation for plasma cell longevity [II]

A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals distinct transcriptional properties and context-dependent binding and regulation of target genes (RNA-Seq)

A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals distinct transcriptional properties and context-dependent binding and regulation of target genes

Multi-hallmark long noncoding RNA maps reveal non-small cell lung cancer vulnerabilities [CRISPRseries]

Distinct leukemogenic mechanism of acute promyelocytic leukemia based on genomic structure of PML-RARα fusion gene

Glycosylated clusterin species facilitate amyloid beta toxicity in human neurons.

Cooperative engagement and subsequent selective displacement of SR proteins define the pre-mRNA 3D structural scaffold for early spliceosome assembly

lncRNAs expression in the liver of large yellow croaker fed with fish oil, soybean oil, olive oil, and palm oil diets

STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion

Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer

The central clock suffices to drive the majority of circulatory metabolic rhythms