Digital reconstruction of spatiotemporal atlas unveils the cellular origins and signaling networks underlying early mouse organogenesis

Single Cell Analysis Reveals The Essential Role of TGFbeta Pathway in Shaping Immune-suppressive Microenvironment and Promoting CRPC Development

Droplet-based RNA sequencing of single cells from injured and regenerating skeletal muscles of young and aged mice

Unveiling Clonal Cell Fate and Differentiation Dynamics: A Hybrid NeuralODE-Gillespie Approach

In situ pharmacological induction of pancreatic beta-cell regeneration by THR-123, a cyclic peptide with BMP-7-like activity

Nephron segmentation and patterning in kidney organoids can be modulated by distinct FGF subfamily members

Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst

Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst [mouse_ERKi_scRNAseq]

Decoding cellular stress states for toxicology using single-cell transcriptomics

Hypoimmunogenic hPSC-derived cardiac organoids for immune evasion and heart repair [scRNA-seq]

Hemolytic stress leads to expansion of erythropoiesis in the spleen

Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

Transcriptional and functional architecture of the whole neutrophil compartment

Co-profiling of in situ RNA-protein interactions and transcriptome in single cells and tissues [scMAPIT-seq]

Chil3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases [scRNA-seq]

Spatio-temporal interaction of immune and renal cells determines glomerular crescent formation in autoimmune kidney disease

Robust generation of photoreceptor-dominant retinal organoids from porcine induced pluripotent stem cells.

A transcriptomic and morphological atlas of protochordate blood reveals divergent immune cell types from vertebrates

Berberine protects against hepatocellular carcinoma progression by regulating intrahepatic T cell heterogeneity

Multiplexed perturbation reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors