In vivo single-cell CRISPR uncovers distinct TNF-α programs in tumor evolution

IL-1b+ tumor-associated macrophages fuel pathogenic inflammation in pancreatic cancer

Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs novel combination cancer therapy strategies

Characterization of cuprizone mouse model at single-cell and spatial transcriptomics level

Spatially restricted immune and microbiota-driven adaptation of the gut

Neuroinflammatory astrocyte subtypes in the mouse brain

Multimodal decoding of human liver regeneration

Spatial analysis of young and old murine lungs exposed to ozone and fibrogenic stress [spatial_ozone]

Spatially restricted immune and microbiota-driven adaptation of the gut [Spatial Transcriptomics]

Zfp281 and Zfp148 control CD4+ T cell thymic development and Th2 functions

Epithelial-Immune Metabolic Codependency Fuels Inflammatory Disease

Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection.

APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge

Hemorrhage-induced NRF2 signaling in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance

Characterization of cuprizone mouse model at single-cell and spatial transcriptomics level[Spatial Transcriptomics]

Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by single-cell transcriptomics

Spatiotemporal hepatocyte heterogeneity impacts in vivo gene engineering

Spatial analysis of murine lungs exposed to fibrogenic stress

Spatiotemporal profiling defines persistence and resistance dynamics during targeted treatment of BRAF-mutant melanoma

Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis