Collagen V regulates renal function after kidney injury and can be targeted to enhance kidney repair in mice [scRNAseq]

Single Cell Map of RORgt Lineage APCs in Early Life

Using an RNA-binding antibody for tumor-directed immunogenic RNA delivery

Molecular Mechanisms Limiting the Therapeutic Window of AAV Gene Therapy in Mouse Models of Blue Cone Monochromacy

Epidermal loss of PRMT5 leads to the emergence of an atypical basal keratinocyte-like cell population and defective skin stratification [multiome]

NAD+ prevents chronic kidney disease by activating renal tubular metabolism - spatial transcriptomics

Spatial genomics reveals cholesterol metabolism as a key factor in immunotherapy resistance in colorectal cancer [Visium]

Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration (fixed scRNA-seq)

T cell-specific RIPK1 ablation results in villus atrophy of the duodenum in mice

Revealing Novel Roles of TLR4 In Macrophage Immunity and Macrophage-Pulmonary Vascular/Lymphatic Endothelial Cell Interactions in Sepsis

Hepatic stellate cells control liver zonation and function via R-spondin 3 [bulkRNAseq_mouse_HSCdepleted]

Hepatic stellate cells control liver zonation and function via R-spondin 3

Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate [coassay_TOXKO]

Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate [coassay_TOXKO_LCMV_Arm_rechalle]

Characterization of macrophages in healthy and diseased livers in mice

Single-cell RNA sequencing of digested whole lungs of mb1Cre-/-ChATfl/fl and mb1Cre+/-Chatfl/fl mice taken before and at 24h after infection with a sublethal dose of Influenza A/Puerto Rico/8/24

Immunosuppressive crosstalk between tumour, myeloid and T cells in an anti-PD-1 plus anti-CTLA-4 therapy resistant mouse ccRCC model [scRNA-seq]

KMT2C Deficiency Drives Luminal Transdifferentiation into Double-Negative Prostate Cancer and Sensitizes to Fatty Acid Synthase Inhibition [scRNA-Seq]

CD45+/Col I+ Fibrocytes: Major Source of Collagen in the Fibrotic Lung, but not in Fibroblast Cultures

Influenza Infection Promotes Lung Accrual of Macrophages with an Obese Adipose Tissue Transcriptomic Signature