Cholinergic regulation of thymocyte negative selection

Increased molecular and functional heterogeneity of hematopoietic stem cells contributes to age-related decline of tissue and body function

IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells

Sox15 is a novel retinal developmental gene that promotes cone photoreceptor differentiation through inhibition of alternative rod photoreceptor fates

Gut-Lung Microbiota Dynamics in Mice Exposed to Nanoplastics

Nuclear Factor NFAT5 Governs Cellular Plasticity-Induced KRAS-Targeted Therapy Resistance in Pancreatic Cancer

Expansion of in vivo HDAd-transduced HSPCs by constitutive expression of tHMGA2 without additional treatment allows for therapeutically relevant transgene expression in HSPC progeny cells without clonal dominance.

Identification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance

A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance [RNA-seq]

SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

DSS-colitis induced in young age accelerates the onset of cognitive defects in Tg2576 mice, a model of Alzheimer disease

Responders to immune checkpoint therapy display early clonal expansion of tumour-infiltrating lymphocytes

Innate-like T cell subset commitment in the murine thymus is independent of TCR characteristics and occurs during proliferation

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF

Experimental tests strongly challenge the evidence of a healthy human blood microbiome

A ketogenic diet can revert acquired resistance to immunotherapy in prostate cancer through β-hydroxybutyrate-mediated inhibition of histone deacetylases

Id3 is required for the maintenance of tissue-infiltrating alloreactive T cells in GVHD but not anti-leukemia responses [ATAC-Seq]

Evaluating the microbiota shift caused by Msc knock-out in wild type and DSS-induced colitis mice

Composition of colonic microbes in mice deficient in intestinal Treg subsets

Single cell analysis of meningeal ectopic lymphoid tissue and lumbar lymph nodes in a spontaneous EAE model