Genome

Pan troglodytes (chimpanzee) The chimpanzee genome sequence is an important tool in understanding primate evolution Lineage: Eukaryota[10796]; Metazoa[5074]; Chordata[2473]; Craniata[2450]; Vertebrata[2450]; Euteleostomi[2430]; Mammalia[687]; Eutheria[513]; Euarchontoglires[207]; Primates[82]; Haplorrhini[60]; Catarrhini[46]; Hominidae[6]; Pan[2]; Pan troglodytes[1]

Pan troglodytes, or chimpanzee, is a primate very closely related to humans. The chimpanzee and other apes are most closely related to humans, followed by Old World monkeys; including the rhesus macaque and baboon. The chimpanzee is an important model to study biology, disease, and evolution. Research with Pan troglodytes has provided More...important insights into cognition, AIDs, hepatitis, diabetes, and other diseases.The genome sequence of the chimpanzee provides an important resource for comparative sequence analysis. Differences between chimpanzee and human genomes will help define the genetic basis of traits that distinguish the human species from other primates. The Pan troglodytes diploid genome is organized in 23 pairs of autosomes and two sex chromosomes. Less...

Summary Sequence data:  genome assemblies: 6; sequence reads: 4  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 3050.4  median protein count: 40465  median GC%: 40.8082 NCBI Annotation Release:  105 Publications (limited to 20 most recent records) A mitogenomic phylogeny of living primates. Finstermeier K, et al. PLoS One 2013 Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics 2011 Sep Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. Hughes JF, et al. Nature 2010 Jan 28 Comparative analysis of chimpanzee and human Y chromosomes unveils complex evolutionary pathway. Kuroki Y, et al. Nat Genet 2006 Feb Initial sequence of the chimpanzee genome and comparison with the human genome. Chimpanzee Sequencing and Analysis Consortium. Nature 2005 Sep 1 Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. Hughes JF, et al. Nature 2005 Sep 1 DNA sequence and comparative analysis of chimpanzee chromosome 22. Watanabe H, et al. Nature 2004 May 27 A complete sequence of the mitochondrial genome of the western lowland gorilla. Xu X, et al. Mol Biol Evol 1996 May The mitochondrial DNA molecule of Sumatran orangutan and a molecular proposal for two (Bornean and Sumatran) species of orangutan. Xu X, et al. J Mol Evol 1996 Nov Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs. Horai S, et al. Proc Natl Acad Sci U S A 1995 Jan 17 Man's place in Hominoidea revealed by mitochondrial DNA genealogy. Horai S, et al. J Mol Evol 1992 Jul Comparisons of ape and human sequences that regulate mitochondrial DNA transcription and D-loop DNA synthesis. Foran DR, et al. Nucleic Acids Res 1988 Jul 11 A comparison of the small ribosomal RNA genes from the mitochondrial DNA of the great apes and humans: sequence, structure, evolution, and phylogenetic implications. Hixson JE, et al. Mol Biol Evol 1986 Jan More...  Representative (genome information for reference and representative genomes) Reference genome:   Pan troglodytes Clint_PTRv2 Submitter: The International Chimpanzee Chromosome 22 Consortium Loc Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr 1 NC_036879.1 CM009238.2 224.24 41.9 7,926 1 46 2,012 3,826 673 Chr 2A NC_036880.1 CM009239.2 108.02 41.1 2,720 1 4 896 1,354 225 Chr 2B NC_036881.1 CM009240.2 128.76 39.6 3,140 1 4 810 1,386 262 Chr 3 NC_036882.1 CM009241.2 196.56 39.7 4,888 1 4 1,339 2,248 436 Chr 4 NC_036883.1 CM009242.2 189.15 38.3 3,223 - 1 1,175 1,816 369 Chr 5 NC_036884.1 CM009243.2 159.32 39.7 2,971 - 18 1,032 1,768 334 Chr 6 NC_036885.1 CM009244.2 168.37 39.7 3,999 1 133 1,249 2,305 435 Chr 7 NC_036886.1 CM009245.2 156.05 40.9 3,783 - 13 1,120 2,035 394 Chr 8 NC_036887.1 CM009246.2 143.34 40.2 2,771 - 6 900 1,515 286 Chr 9 NC_036888.1 CM009247.2 110.51 41.5 3,241 - 3 795 1,496 278 Chr 10 NC_036889.1 CM009248.2 129.81 41.8 3,702 - 3 796 1,539 279 Chr 11 NC_036890.1 CM009249.2 130.78 41.6 4,957 - 14 939 2,276 384 Chr 12 NC_036891.1 CM009250.2 131 40.9 4,362 - 10 1,061 1,985 346 Chr 13 NC_036892.1 CM009251.2 95.6 38.6 1,492 - 4 622 890 172 Chr 14 NC_036893.1 CM009252.2 87.72 41.0 2,526 - 19 800 1,406 231 Chr 15 NC_036894.1 CM009253.2 80.52 42.3 2,478 - 8 980 1,347 244 Chr 16 NC_036895.1 CM009254.2 75.91 44.9 3,013 - 28 623 1,333 164 Chr 17 NC_036896.1 CM009255.2 76.55 45.7 4,392 - 34 893 1,925 241 Chr 18 NC_036897.1 CM009256.2 74.77 39.9 1,344 - 1 514 708 142 Chr 19 NC_036898.1 CM009257.2 56.73 48.4 4,949 - 7 834 1,997 213 Chr 20 NC_036899.1 CM009258.2 64.04 44.2 2,128 2 - 573 1,026 159 Chr 21 NC_036900.1 CM009259.2 33.23 41.1 808 - 1 303 471 76 Chr 22 NC_036901.1 CM009260.2 33.7 48.2 1,885 - - 471 823 102 Chr X NC_036902.1 CM009261.2 151.58 39.7 2,737 1 2 697 1,646 444 Chr Y NC_006492.4 - 26.35 40.6 119 3 - 74 271 154 MT NC_001643.1 - 0.02 43.7 13 2 22 - 37 - Un - . - 217.77 38.1 1,244 3 25 792 1,581 552 Chromosomes Click on chromosome name to open Genome Data Viewer External Resources Washington University Genome Sequencing Center Broad Institute CHGCS CHORI BAC library Ensembl Great Ape Genome Project IPBIR KRIBB National Primate Research Centers Primate Cytogenetics UCSC browser White Paper #1 White Paper #2