Genome

Canis lupus familiaris (dog) dog Lineage: Eukaryota[10856]; Metazoa[5115]; Chordata[2487]; Craniata[2464]; Vertebrata[2464]; Euteleostomi[2443]; Mammalia[687]; Eutheria[513]; Laurasiatheria[286]; Carnivora[76]; Caniformia[49]; Canidae[11]; Canis[3]; Canis lupus[3]; Canis lupus familiaris[1]

The dog, Canis lupus familiaris, is a useful model organism for medical research due to extensive genetic diversity and morphological variation within the species and to aggressive breeding practices that have resulted in inbred populations of dogs. Many breeds of dog are particularly susceptible to inherited diseases that are also common in More...humans, such as cancer, heart disease, rheumatoid arthritis, autoimmune disorders, deafness, and blindness. The size of the haploid dog genome is estimated to be 2445 Mb. The diploid genome is organized in 38 pairs of autosomes and two sex chromosomes. Less...

Summary Sequence data:  genome assemblies: 15; sequence reads: 31  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 2344.99  median protein count: 64557  median GC%: 41.2171 NCBI Annotation Release:  106 Publications (limited to 20 most recent records) Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. Field MA, et al. Gigascience 2020 Apr 1 Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer. Jeong YH, et al. Sci Rep 2016 Aug 9 Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature 2005 Dec 8 The dog genome: survey sequencing and comparative analysis. Kirkness EF, et al. Science 2003 Sep 26 The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome. Kim KS, et al. Mol Phylogenet Evol 1998 Oct More...  Representative (genome information for reference and representative genomes) Reference genome:   Canis lupus familiaris Dog10K_Boxer_Tasha Submitter: Dog Genome Sequencing Consortium Loc Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr 1 NC_006583.4 CM000001.4 122.01 41.7 3,951 - 9 1,789 2,306 270 Chr 2 NC_006584.4 CM000002.4 82.04 43.1 2,488 1 8 1,357 1,556 143 Chr 3 NC_006585.4 CM000003.4 94.33 40.6 1,637 - 7 1,174 1,251 185 Chr 4 NC_006586.4 CM000004.4 87.91 40.4 1,712 5 3 1,239 1,326 187 Chr 5 NC_006587.4 CM000005.4 88.91 44.2 3,343 - 25 1,468 1,846 153 Chr 6 NC_006588.4 CM000006.4 80.21 43.2 2,753 - 27 1,212 1,670 146 Chr 7 NC_006589.4 CM000007.4 80.42 41.0 2,262 4 6 1,201 1,413 175 Chr 8 NC_006590.4 CM000008.4 73.59 40.7 1,909 - 5 1,152 1,428 189 Chr 9 NC_006591.4 CM000009.4 60.32 46.3 3,446 - 23 1,157 1,828 117 Chr 10 NC_006592.4 CM000010.4 69.22 42.9 2,020 - 9 1,222 1,327 153 Chr 11 NC_006593.4 CM000011.4 72.83 40.4 1,670 - 10 983 1,164 141 Chr 12 NC_006594.4 CM000012.4 72.3 39.0 1,746 - 2 803 1,159 179 Chr 13 NC_006595.4 CM000013.4 62.9 40.2 1,291 - 3 817 899 132 Chr 14 NC_006596.4 CM000014.4 60.43 38.8 1,213 - 7 731 881 135 Chr 15 NC_006597.4 CM000015.4 64.39 40.4 1,652 1 18 1,030 1,114 126 Chr 16 NC_006598.4 CM000016.4 54.56 41.5 1,392 - 17 739 953 120 Chr 17 NC_006599.4 CM000017.4 63.74 41.8 1,813 - 30 1,012 1,230 142 Chr 18 NC_006600.4 CM000018.4 54.36 43.0 2,150 - 10 777 1,270 114 Chr 19 NC_006601.4 CM000019.4 52.99 38.3 654 - 2 573 554 97 Chr 20 NC_006602.4 CM000020.4 57.98 44.5 2,931 - 6 872 1,549 130 Chr 21 NC_006603.4 CM000021.4 50.23 40.2 1,341 - 3 589 963 139 Chr 22 NC_006604.4 CM000022.4 61.82 38.0 777 - 5 656 677 116 Chr 23 NC_006605.4 CM000023.4 52.41 40.0 1,157 - 5 651 774 123 Chr 24 NC_006606.4 CM000024.4 46.83 44.5 1,679 - 1 745 967 70 Chr 25 NC_006607.4 CM000025.4 51.91 41.4 1,466 1 5 756 897 113 Chr 26 NC_006608.4 CM000026.4 38.73 45.5 1,590 - 10 596 837 59 Chr 27 NC_006609.4 CM000027.5 46.28 40.3 1,788 - 2 556 925 117 Chr 28 NC_006610.4 CM000028.4 41.27 43.7 1,294 - - 590 719 65 Chr 29 NC_006611.4 CM000029.4 40.89 38.0 574 - 5 459 509 79 Chr 30 NC_006612.4 CM000030.4 40.07 41.5 1,358 - 7 550 774 90 Chr 31 NC_006613.4 CM000031.4 39.09 39.6 627 - 1 478 533 65 Chr 32 NC_006614.4 CM000032.5 41.86 38.5 748 - - 446 521 105 Chr 33 NC_006615.4 CM000033.4 31.42 39.3 792 - 2 479 477 56 Chr 34 NC_006616.4 CM000034.4 51.11 41.3 688 - 2 582 592 62 Chr 35 NC_006617.4 CM000035.4 26.04 41.4 505 - 99 354 567 67 Chr 36 NC_006618.4 CM000036.4 30.72 38.7 565 - 2 448 432 56 Chr 37 NC_006619.4 CM000037.4 31.75 40.4 795 - 2 547 508 49 Chr 38 NC_006620.4 CM000038.4 23.97 41.1 619 - 25 381 467 49 Chr X NC_006621.4 CM000039.4 108.81 40.3 1,937 - 11 710 1,539 394 MT NC_002008.4 CM023446.1 0.02 39.7 13 2 22 - 37 - Un - . - 2.13 42.8 1 - - 2 3 1 Chromosomes Click on chromosome name to open Genome Data Viewer External Resources Animal Health Trust Dog DNA Testing Canine BAC Library Canine Genetic Linkage Map Canine Sequencing White Paper Cytogenetics and Canine Cancer, NC State DFCI Gene Index Dog Genome Sequencing Project - Broad Dog Olfactory Receptors NHGRI Dog Genome Project NISC Comparative Vertebrate Sequencing Online Mendelian Inheritance in Animals The Canine Radiation Hybrid Project The FHCRC Dog Genome Project