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Information by organism

Canis lupus familiaris (dog)
Reference genome: Canis lupus familiaris (assembly CanFam3.1)
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ID: 85

Organism Overview ; Genome Assembly and Annotation report [150] ; Organelle Annotation Report [5]

Organism Image

Canis lupus familiaris (dog)

dog

Lineage: Eukaryota[5961]; Metazoa[2392]; Chordata[1377]; Craniata[1356]; Vertebrata[1356]; Euteleostomi[1342]; Mammalia[421]; Eutheria[412]; Laurasiatheria[235]; Carnivora[54]; Caniformia[35]; Canidae[5]; Canis[2]; Canis lupus[2]; Canis lupus familiaris[1]

The dog, Canis lupus familiaris, is a useful model organism for medical research due to extensive genetic diversity and morphological variation within the species and to aggressive breeding practices that have resulted in inbred populations of dogs. Many breeds of dog are particularly susceptible to inherited diseases that are also common in More...

Summary

Sequence data:

genome assemblies: 150; sequence reads: 21

(See Genome Assembly and Annotation report)

Statistics:

median total length (Mb): 2370.95

median protein count: 58776

median GC%: 41.2033

NCBI Annotation Release:

Publications (limited to 20 most recent records)

Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. Field MA, et al. Gigascience 2020 Apr 1
Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic. Ameen C, et al. Proc Biol Sci 2019 Dec 4
Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer. Jeong YH, et al. Sci Rep 2016 Aug 9
Characterization of HOX gene expression in canine mammary tumour cell lines from spontaneous tumours. DeInnocentes P, et al. Vet Comp Oncol 2015 Sep
Tandem repeats modify the structure of the canine CD1D gene. Looringh van Beeck FA, et al. Anim Genet 2013 Jun
Derived variants at six genes explain nearly half of size reduction in dog breeds. Rimbault M, et al. Genome Res 2013 Dec
The dynamic role of cardiac myosin binding protein-C during ischemia. Decker RS, et al. J Mol Cell Cardiol 2012 May
Experimental validation of in silico predicted KCNA1, KCNA2, KCNA6 and KCNQ2 genes for association studies of peripheral nerve hyperexcitability syndrome in Jack Russell Terriers. Van Poucke M, et al. Neuromuscul Disord 2012 Jun
The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer. Shearin AL, et al. Cancer Epidemiol Biomarkers Prev 2012 Jul
A novel mitofusin 2 mutation causes canine fetal-onset neuroaxonal dystrophy. Fyfe JC, et al. Neurogenetics 2011 Aug
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Goldstein O, et al. Mol Vis 2010 Aug 11
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure. El-Armouche A, et al. J Mol Cell Cardiol 2007 Aug
Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog. Jensen TN, et al. Eur J Pharmacol 2006 May 24
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature 2005 Dec 8
The dog genome: survey sequencing and comparative analysis. Kirkness EF, et al. Science 2003 Sep 26
Links between Fer tyrosine kinase expression levels and prostate cell proliferation. Allard P, et al. Mol Cell Endocrinol 2000 Jan 25
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. De Deken X, et al. J Biol Chem 2000 Jul 28
A method for the large-scale cloning of nuclear proteins and nuclear targeting sequences on a functional basis. Pichon B, et al. Anal Biochem 2000 Sep 10
The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome. Kim KS, et al. Mol Phylogenet Evol 1998 Oct
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Lowe TM, et al. Nucleic Acids Res 1997 Mar 1

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