Canis lupus familiaris (ID 85) - Genome

Canis lupus familiaris (dog)
Reference genome: Canis lupus familiaris (assembly CanFam3.1)
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ID: 85

Organism Overview ; Genome Assembly and Annotation report [4] ; Organelle Annotation Report [1]

Canis lupus familiaris (dog)

dog

Lineage: Eukaryota[3399]; Metazoa[1117]; Chordata[547]; Craniata[537]; Vertebrata[537]; Euteleostomi[528]; Mammalia[185]; Eutheria[179]; Laurasiatheria[94]; Carnivora[25]; Caniformia[19]; Canidae[4]; Canis[2]; Canis lupus[2]; Canis lupus familiaris[1]

The dog, Canis lupus familiaris, is a useful model organism for medical research due to extensive genetic diversity and morphological variation within the species and to aggressive breeding practices that have resulted in inbred populations of dogs. Many breeds of dog are particularly susceptible to inherited diseases that are also common in More...

Summary

Sequence data:

genome assemblies: 4; sequence reads: 19

(See Genome Assembly and Annotation report)

Statistics:

median total length (Mb): 2254.63

median protein count: 58776

median GC%: 41.1

NCBI Annotation Release:

105

Publications

Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer. Jeong YH, et al. Sci Rep 2016 Aug 9
Characterization of HOX gene expression in canine mammary tumour cell lines from spontaneous tumours. DeInnocentes P, et al. Vet Comp Oncol 2015 Sep
Tandem repeats modify the structure of the canine CD1D gene. Looringh van Beeck FA, et al. Anim Genet 2013 Jun
Derived variants at six genes explain nearly half of size reduction in dog breeds. Rimbault M, et al. Genome Res 2013 Dec
The dynamic role of cardiac myosin binding protein-C during ischemia. Decker RS, et al. J Mol Cell Cardiol 2012 May
Experimental validation of in silico predicted KCNA1, KCNA2, KCNA6 and KCNQ2 genes for association studies of peripheral nerve hyperexcitability syndrome in Jack Russell Terriers. Van Poucke M, et al. Neuromuscul Disord 2012 Jun
The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer. Shearin AL, et al. Cancer Epidemiol Biomarkers Prev 2012 Jul
A novel mitofusin 2 mutation causes canine fetal-onset neuroaxonal dystrophy. Fyfe JC, et al. Neurogenetics 2011 Aug
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Goldstein O, et al. Mol Vis 2010 Aug 11
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure. El-Armouche A, et al. J Mol Cell Cardiol 2007 Aug
Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog. Jensen TN, et al. Eur J Pharmacol 2006 May 24
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature 2005 Dec 8
The dog genome: survey sequencing and comparative analysis. Kirkness EF, et al. Science 2003 Sep 26
Links between Fer tyrosine kinase expression levels and prostate cell proliferation. Allard P, et al. Mol Cell Endocrinol 2000 Jan 25
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. De Deken X, et al. J Biol Chem 2000 Jul 28
A method for the large-scale cloning of nuclear proteins and nuclear targeting sequences on a functional basis. Pichon B, et al. Anal Biochem 2000 Sep 10
The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome. Kim KS, et al. Mol Phylogenet Evol 1998 Oct
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Lowe TM, et al. Nucleic Acids Res 1997 Mar 1
Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane. Voigt S, et al. J Cell Biol 1996 Jul
A protein of the endoplasmic reticulum involved early in polypeptide translocation. Görlich D, et al. Nature 1992 May 7

More...

Representative (genome information for reference and representative genomes)

Reference genome:

Canis lupus familiaris CanFam3.1

Submitter: Dog Genome Sequencing Consortium

Type	Name	RefSeq	INSDC	Size (Mb)	GC%	Protein	rRNA	tRNA	Other RNA	Gene	Pseudogene
	master WGS	-	AAEX00000000.3	2,392.7	41.3	-	-	-	-	-	-

Chr	1	NC_006583.3	CM000001.3	122.68	41.6	3,540	-	8	1,312	2,078	257

Chr	2	NC_006584.3	CM000002.3	85.43	42.8	2,231	-	6	986	1,384	152

Chr	3	NC_006585.3	CM000003.3	91.89	40.3	1,491	-	5	918	1,076	177

Chr	4	NC_006586.3	CM000004.3	88.28	40.4	1,579	-	3	892	1,142	183

Chr	5	NC_006587.3	CM000005.3	88.92	44.2	3,124	-	26	1,036	1,652	147

Chr	6	NC_006588.3	CM000006.3	77.57	42.6	2,651	-	26	898	1,514	155

Chr	7	NC_006589.3	CM000007.3	80.97	41.0	2,101	-	7	919	1,253	170

Chr	8	NC_006590.3	CM000008.3	74.33	40.6	1,712	-	6	845	1,227	198

Chr	9	NC_006591.3	CM000009.3	61.07	46.0	3,224	-	19	886	1,651	106

Chr	10	NC_006592.3	CM000010.3	69.33	42.7	1,868	-	8	856	1,190	153

Chr	11	NC_006593.3	CM000011.3	74.39	40.2	1,640	-	9	723	1,024	145

Chr	12	NC_006594.3	CM000012.3	72.5	39.0	1,705	-	3	593	1,024	165

Chr	13	NC_006595.3	CM000013.3	63.24	40.0	1,164	-	3	620	794	126

Chr	14	NC_006596.3	CM000014.3	60.97	38.8	1,099	-	5	566	799	141

Chr	15	NC_006597.3	CM000015.3	64.19	40.2	1,534	-	12	788	968	122

Chr	16	NC_006598.3	CM000016.3	59.63	41.0	1,305	-	16	556	870	119

Chr	17	NC_006599.3	CM000017.3	64.29	41.7	1,766	-	31	804	1,129	123

Chr	18	NC_006600.3	CM000018.3	55.84	42.8	1,988	-	10	595	1,214	125

Chr	19	NC_006601.3	CM000019.3	53.74	38.4	568	-	2	457	469	99

Chr	20	NC_006602.3	CM000020.3	58.13	44.3	2,673	-	6	604	1,377	123

Chr	21	NC_006603.3	CM000021.3	50.86	40.2	1,367	-	3	439	871	170

Chr	22	NC_006604.3	CM000022.3	61.44	37.9	712	-	4	556	591	117

Chr	23	NC_006605.3	CM000023.3	52.29	39.9	1,006	-	3	512	667	124

Chr	24	NC_006606.3	CM000024.3	47.7	44.5	1,550	-	2	560	890	74

Chr	25	NC_006607.3	CM000025.3	51.63	41.4	1,305	-	4	574	798	109

Chr	26	NC_006608.3	CM000026.3	38.96	45.4	1,478	-	10	466	794	76

Chr	27	NC_006609.3	CM000027.3	45.88	40.1	1,662	-	3	464	858	128

Chr	28	NC_006610.3	CM000028.3	41.18	43.5	1,194	-	-	461	642	70

Chr	29	NC_006611.3	CM000029.3	41.85	38.2	538	-	5	366	474	91

Chr	30	NC_006612.3	CM000030.3	40.21	41.4	1,210	-	5	441	681	86

Chr	31	NC_006613.3	CM000031.3	39.9	39.5	644	-	-	357	486	71

Chr	32	NC_006614.3	CM000032.3	38.81	36.9	706	-	-	302	464	121

Chr	33	NC_006615.3	CM000033.3	31.38	39.2	694	-	2	330	414	57

Chr	34	NC_006616.3	CM000034.3	42.12	40.4	627	-	2	380	471	57

Chr	35	NC_006617.3	CM000035.3	26.53	41.4	528	-	102	272	529	66

Chr	36	NC_006618.3	CM000036.3	30.81	38.6	551	-	2	342	376	57

Chr	37	NC_006619.3	CM000037.3	30.9	40.2	712	-	3	438	453	45

Chr	38	NC_006620.3	CM000038.3	23.91	41.0	485	-	28	296	442	63

Chr	X	NC_006621.3	CM000039.3	123.87	40.3	2,338	-	6	619	1,586	472

	MT	NC_002008.4	U96639.2	0.02	39.7	13	2	22	-	13	-

Un	-	.	-	83.33	47.2	493	-	2	146	474	48

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