Genome

Dengue virus Dengue virus overview Lineage: Viruses[32585]; Riboviria[7831]; Orthornavirae[6386]; Kitrinoviricota[1226]; Flasuviricetes[232]; Amarillovirales[232]; Flaviviridae[232]; Orthoflavivirus[106]; Orthoflavivirus denguei[1]; Dengue virus[1]

Broad's Viral Genomics Initiative focuses on four viruses: HCV, HIV, Dengue, and WNV. The scale and specific aims of each project varies, but they all are centered on understanding sequence variation as it relates to disease outcome and how the viruses evolve under host immune pressure.

Summary Sequence data:  genome assemblies: 10; sequence reads: 5 Statistics:  median total length (Mb): 0.0107015  median protein count: 1  median GC%: 46.7 Publications (limited to 20 most recent records) Genome-wide patterns of intrahuman dengue virus diversity reveal associations with viral phylogenetic clade and interhost diversity. Parameswaran P, et al. J Virol 2012 Aug Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor. Orozco S, et al. J Gen Virol 2012 Oct  Representative (genome information for reference and representative genomes) Reference genome:   dengue virus type 2 Type Name RefSeq INSDC Size (Kb) GC% Protein Gene Chr Unknown NC_001474.2 U87411.1 10.72 45.8 1 1 External Resources Broad Institute Dengue virus portal