Escherichia coli. This organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E.coli is easily grown in a laboratory setting and is readily amenable to genetic manipulation making it one of the most
More...studied prokaryotic model organisms. E.coli K-12 is the most widely studied strain of E. coli and serves as a reference for this species. E. coli is also one of the most diverse microbial species, containing both pathogenic and non-pathogenic strains. Pathogenic E. coli can cause urinary tract infections, neonatal meningitis, and many, often severe, intestinal diseases. Pathogenic strains often have virulence factors encoded on extrachromosomal plasmids or within bacteriophages and distinct DNA segments termed pathogenicity islands (PAIs). PAIs are likely to have been transferred horizontally and may even have integrated into the chromosome through bacteriophage or plasmid integration or transposition. These virulence factors have often been transferred from closely related, highly pathogenic, Shigella species. Among other virulence factors, enteroinvasive E. coli share an invasion plasmid with Shigella.Reference strains from the pathogenic E. coli are the urinary tract pathogens Escherichia coli IAI39 and Escherichia coli UMN026, Escherichia coli O157:H7 str. Sakai which causes hemorrhagic colitis, Escherichia coli O83:H1 str. NRG 857C which is implicated in Crohn's Disease, and Escherichia coli O104:H4 str. 2011C-3493 which cause hemolytic uremic syndrome. Less...- Pathogenicity of Shiga toxin-producing Escherichia coli (STEC) from wildlife: Should we care? Dias D, et al. Sci Total Environ 2022 Mar 15
- Multicenter Evaluation of the Acuitas AMR Gene Panel for Detection of an Extended Panel of Antimicrobial Resistance Genes among Bacterial Isolates. Simner PJ, et al. J Clin Microbiol 2022 Mar 16
- Isolation and Characterization of Novel Lytic Phages Infecting Multidrug-Resistant Escherichia coli. Vera-Mansilla J, et al. Microbiol Spectr 2022 Feb 23
- Prevalence and antimicrobial susceptibility of CTX-M-type-producing Escherichia coli from a wildlife zoo in China. Zeng Z, et al. Vet Med Sci 2022 May
- Population Diversity of Antibiotic Resistant Enterobacterales in Samples From Wildlife Origin in Senegal: Identification of a Multidrug Resistance Transposon Carrying bla CTX-M-15 in Escherichia coli. Abdallah R, et al. Front Microbiol 2022
- Occurrence and transfer characteristics of blaCTX-M genes among Escherichia coli in anaerobic digestion systems treating swine waste. Tian T, et al. Sci Total Environ 2022 Aug 15
- High Carriage of Extended-Spectrum, Beta Lactamase-Producing, and Colistin-Resistant Enterobacteriaceae in Tibetan Outpatients with Diarrhea. Li Z, et al. Antibiotics (Basel) 2022 Apr 11
- Clonal and plasmid-mediated flow of ESBL/AmpC genes in Escherichia coli in a commercial laying hen farm. Aldea I, et al. Vet Microbiol 2022 Jul
- Clonal relationship of tet(X4)-positive Escherichia coli ST761 isolates between animals and humans. Zhai W, et al. J Antimicrob Chemother 2022 Jul 28
- Transmissibility and Persistence of the Plasmid-Borne Mobile Colistin Resistance Gene, mcr-1, Harbored in Poultry-Associated E. coli. Al Mana H, et al. Antibiotics (Basel) 2022 Jun 7
- Identification of Mobile Colistin Resistance Gene mcr-10 in Disinfectant and Antibiotic Resistant Escherichia coli from Disinfected Tableware. Zhang S, et al. Antibiotics (Basel) 2022 Jul 1
- Antimicrobial resistance surveillance of Escherichia coli from chickens in the Qinghai Plateau of China. Tang B, et al. Front Microbiol 2022
- Characterization of Adherent-Invasive Escherichia coli (AIEC) Outer Membrane Proteins Provides Potential Molecular Markers to Screen Putative AIEC Strains. Saitz W, et al. Int J Mol Sci 2022 Aug 12
- Whole Genome Sequencing and Molecular Analysis of Carbapenemase-Producing Escherichia coli from Intestinal Carriage in Elderly Inpatients. Giufrè M, et al. Microorganisms 2022 Aug 3
- Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies). Hernández-García M, et al. Microbiol Spectr 2022 Oct 26
- Escherichia coli ST224 and IncF/blaCTX-M-55 plasmids drive resistance to extended-spectrum cephalosporins in poultry flocks in Parana, Brazil. Dos Anjos Adur M, et al. Int J Food Microbiol 2022 Nov 2
- Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome. Ravi A, et al. Commun Biol 2022 Sep 8
- Genomic characterization of multidrug-resistance gene cfr in Escherichia coli recovered from food animals in Eastern China. Tang B, et al. Front Microbiol 2022
- Lactic Acid Resistance and Population Structure of Escherichia coli from Meat Processing Environment. Fang Y, et al. Microbiol Spectr 2022 Oct 26
- HiFi metagenomic sequencing enables assembly of accurate and complete genomes from human gut microbiota. Kim CY, et al. Nat Commun 2022 Oct 26
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Reference genomes:  
Escherichia coli str. K-12 substr. MG1655Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated |
Type
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Name
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RefSeq
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INSDC
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Size (Mb)
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GC%
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Protein
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rRNA
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tRNA
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Other RNA
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Gene
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Pseudogene
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| Chr | - | NC_000913.3 | U00096.3 | 4.64 | 50.8 | 4,298 | 22 | 86 | 99 | 4,639 | 145 | |
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Escherichia coli O157:H7 str. Sakai
Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated Phenotype: Disease:Hemorrhagic colitis
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