Escherichia coli. This organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E.coli is easily grown in a laboratory setting and is readily amenable to genetic manipulation making it one of the most
More...studied prokaryotic model organisms. E.coli K-12 is the most widely studied strain of E. coli and serves as a reference for this species. E. coli is also one of the most diverse microbial species, containing both pathogenic and non-pathogenic strains. Pathogenic E. coli can cause urinary tract infections, neonatal meningitis, and many, often severe, intestinal diseases. Pathogenic strains often have virulence factors encoded on extrachromosomal plasmids or within bacteriophages and distinct DNA segments termed pathogenicity islands (PAIs). PAIs are likely to have been transferred horizontally and may even have integrated into the chromosome through bacteriophage or plasmid integration or transposition. These virulence factors have often been transferred from closely related, highly pathogenic, Shigella species. Among other virulence factors, enteroinvasive E. coli share an invasion plasmid with Shigella.Reference strains from the pathogenic E. coli are the urinary tract pathogens Escherichia coli IAI39 and Escherichia coli UMN026, Escherichia coli O157:H7 str. Sakai which causes hemorrhagic colitis, Escherichia coli O83:H1 str. NRG 857C which is implicated in Crohn's Disease, and Escherichia coli O104:H4 str. 2011C-3493 which cause hemolytic uremic syndrome. Less...- Characterization of unconventional pathogenic Escherichia coli isolated from bloodstream infection: virulence beyond the opportunism. Santos ACM, et al. Braz J Microbiol 2023 Mar
- First report on the molecular characteristics of mcr-1 colistin resistant E. coli isolated from retail broiler meat in Bangladesh. Ali MW, et al. Int J Food Microbiol 2023 Mar 2
- Adaptive Evolution Compensated for the Plasmid Fitness Costs Brought by Specific Genetic Conflicts. Li F, et al. Pathogens 2023 Jan 13
- Resistance to critically important antibiotics in hospital wastewater from the largest Croatian city. Puljko A, et al. Sci Total Environ 2023 Apr 20
- Complete Genome Sequences of Extraintestinal Pathogenic Escherichia coli Clinical Isolates from Danish Ulcerative Colitis Patients. Meski S, et al. Microbiol Resour Announc 2023 Feb 16
- A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase. Dhindwal P, et al. Proc Natl Acad Sci U S A 2023 Feb 21
- Alteration of a Shiga toxin-encoding phage associated with a change in toxin production level and disease severity in Escherichia coli. Miyata T, et al. Microb Genom 2023 Feb
- In vitro activity of apramycin against 16S-RMTase-producing Gram-negative isolates. Caméléna F, et al. J Glob Antimicrob Resist 2023 Feb 22
- Characterization of NDM-5-Producing Escherichia coli Strains Isolated from Pediatric Patients with Bloodstream Infections in a Chinese Hospital. Huang L, et al. Genes (Basel) 2023 Feb 18
- Back to Basics: A Simplified Improvement to Multiple Displacement Amplification for Microbial Single-Cell Genomics. Sobol MS, et al. Int J Mol Sci 2023 Feb 21
- Distribution of Extremely Heat-Resistant Escherichia coli in the Beef Production and Processing Continuum. Guragain M, et al. J Food Prot 2023 Jan
- Draft genome sequences of rare Lelliottia nimipressuralis strain MEZLN61 and two Enterobacter kobei strains MEZEK193 and MEZEK194 carrying mobile colistin resistance gene mcr-9 isolated from wastewater in South Africa. El Zowalaty ME, et al. J Glob Antimicrob Resist 2023 Mar 21
- Adherent-invasive Escherichia coli associated with granulomatous colitis and extraintestinal dissemination in a Sphynx cat. Tuomisto L, et al. Vet Pathol 2023 May
- Complete sequence of a new conjugative multidrug-resistance encoding IncFII/IncFIA/IncFIB plasmid carrying NDM-6 metallo-β-lactamase from pathogenic Escherichia coli sequence type 167 isolated from sewage in Norway. Grevskott DH, et al. J Glob Antimicrob Resist 2023 Apr 21
- Occurrence and genetic characterization of Shiga toxin-producing Escherichia coli on bovine and pork carcasses and the environment from transport trucks. Colello R, et al. World J Microbiol Biotechnol 2023 Apr 28
- Virotyping and genetic antimicrobial susceptibility testing of porcine ETEC/STEC strains and associated plasmid types. Vereecke N, et al. Front Microbiol 2023
- Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic. Zelendova M, et al. Front Microbiol 2023
- Complete sequence of classic F-type plasmid pRK100 shows unique conservation over time and geographic location. Starčič Erjavec M, et al. Plasmid 2022 Jan-Mar
- Antimicrobial resistance surveillance of Escherichia coli from chickens in the Qinghai Plateau of China. Tang B, et al. Front Microbiol 2022
- Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies). Hernández-García M, et al. Microbiol Spectr 2022 Oct 26
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Reference genomes:  
Escherichia coli str. K-12 substr. MG1655Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated |
Type
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Name
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RefSeq
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INSDC
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Size (Mb)
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GC%
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Protein
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rRNA
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tRNA
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Other RNA
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Gene
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Pseudogene
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| Chr | - | NC_000913.3 | U00096.3 | 4.64 | 50.8 | 4,298 | 22 | 86 | 99 | 4,639 | 145 | |
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Escherichia coli O157:H7 str. Sakai
Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated Phenotype: Disease:Hemorrhagic colitis
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