Genome

Mycobacterium marinum Causes systemic infection in fish and skin infections in humans Lineage: Bacteria[34354]; Actinobacteria[4409]; Corynebacteriales[668]; Mycobacteriaceae[248]; Mycobacterium[128]; Mycobacterium ulcerans group[5]; Mycobacterium marinum[1]

Mycobacterium. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high More...genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall.Mycobacterium marinum. Mycobacterium marinum is commonly found in fresh and salt water in North America. This bacterium, a close relative of M. tuberculosis, causes a tuberculosis-like disease in frogs, fish and other cold-blooded animals, and a peripheral granulomatous disease in humans. Human infections can be persistent and may lead to systemic infection and arthritis. M. marinum is photochromogenic, i.e. it produces bright yellow pigmentation (mainly beta-carotene) upon exposure to visible light. Infection is followed by a 2-8 week incubation period resulting in suppuration (pus) and organized ulcerating granulomas (tumorous lesions), predominantly localized in lymphatic and tendon sheaths, and cooler body tissues in the extremities. Less...

Summary Sequence data:  genome assemblies: 51  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 6.02934  median protein count: 5147  median GC%: 65.6 Publications (limited to 20 most recent records) Disseminated Mycobacterium marinum in Human Immunodeficiency Virus Unmasked by Immune Reconstitution Inflammatory Syndrome. Manion M, et al. J Infect Dis 2021 Aug 2 Complete Genome Sequence of Mycobacterium marinum ATCC 927T, Obtained Using Nanopore and Illumina Sequencing Technologies. Yoshida M, et al. Genome Announc 2018 May 17 Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing. Das S, et al. Sci Rep 2018 Aug 13 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. Stinear TP, et al. Genome Res 2008 May Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones. Pidot SJ, et al. BMC Genomics 2008 Oct 7 More...  Representative (genome information for reference and representative genomes) Reference genome:   Mycobacterium marinum ASM1674529v1 Submitter: NIH Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr - NZ_CP058277.1 CP058277.1 6.32 65.8 5,110 6 47 3 5,317 151 Dendrogram (based on genomic BLAST)