Mycobacterium ulcerans. Infection by
Mycobacterium ulcerans causes the formation of skin ulcers which, if left untreated, can lead to extensive scarring and/or amputation. This disease, called Buruli or Bairnsdale ulcer, is prevalent throughout much of Africa and Asia.
Mycobacterium ulcerans produces a cytotoxin, mycolactone,
More...which causes the destruction of skin tissue seen in this disease. This organism is resistant to antibiotics and treatment involves the surgical removal of infected tissues. Mycobacterium ulcerans has been identified in stagnant water and in aquatic insects. It is thought that spread of this disease is through contact with water or through the bite of these aquatic insects. Less...