Genome

Mycobacterium intracellulare Mycobacterium intracellulare overview Lineage: Bacteria[36038]; Actinomycetota[4664]; Actinomycetes[4256]; Mycobacteriales[706]; Mycobacteriaceae[249]; Mycobacterium[118]; Mycobacterium avium complex (MAC)[14]; Mycobacterium intracellulare[4]

Mycobacterium. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high More...genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium intracellulare. Mycobacterium intracellulare is a member of the Mycobacterium avium complex (MAC). These organisms cause tuberculosis in birds, and pulmonary and disseminated infections in immunocompromized humans. Mycobacterium intracellulare is also an important contributor to MAC-associated pulmonary infections in immunocompetent patients. Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Mycobacterium intracellulare can also be isolated from the environment and, like other environmental organisms, is able to form and survive in biofilms. Less...

Summary Sequence data:  genome assemblies: 58; sequence reads: 3  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 5.53538  median protein count: 5107  median GC%: 67.9367 Publications (limited to 20 most recent records) FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science. Sichtig H, et al. Nat Commun 2019 Jul 25 Complete Genome Sequence of Mycobacterium abscessus subsp. bolletii. Caverly LJ, et al. Genome Announc 2016 Jun 9 Complete genome sequence of Mycobacterium intracellulare strain ATCC 13950(T). Kim BJ, et al. J Bacteriol 2012 May Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-02. Kim BJ, et al. J Bacteriol 2012 May Whole-genome sequence of the hypervirulent clinical strain Mycobacterium intracellulare M.i.198. Tateishi Y, et al. J Bacteriol 2012 Nov More...  Representative (genome information for reference and representative genomes) Reference genome:   Mycobacterium intracellulare ASM2073600v1 Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr - NZ_CP085945.1 CP085945.1 5.62 67.9 5,132 3 45 3 5,275 92 Plsm unnamed NZ_CP085946.1 CP085946.1 0.02 65.3 22 - - - 22 - Dendrogram (based on genomic BLAST)