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    Fmr1 synaptic functional regulator FMR1 [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 657873, updated on 2-Apr-2025
    Gene symbol
    Fmr1
    Gene description
    synaptic functional regulator FMR1
    Locus tag
    TcasGA2_TC003774
    See related
    EnsemblRapid:GeneID_657873
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Orthologs
    fruit fly all
    NEW
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    See Fmr1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 7 NC_087400.1 (7274207..7287071)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG3 NC_007418.3 (17786407..17799246, complement)

    Chromosome 7 - NC_087400.1Genomic Context describing neighboring genes Neighboring gene zona pellucida domain-containing protein miniature Neighboring gene transmembrane protein dusky Neighboring gene uncharacterized LOC135266722 Neighboring gene WD repeat-containing protein 44 Neighboring gene lipocalin/cytosolic fatty acid-binding protein Karl Neighboring gene uncharacterized LOC657955 Neighboring gene methyl-CpG-binding domain protein 2 Neighboring gene leucine-rich repeat-containing protein 15-like

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anterograde axonal transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of dendrite morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of dendritic spine development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mRNA stability IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of modification of synaptic structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    RNA-binding protein FXR1; fragile X messenger ribonucleoprotein 1 homolog
    Names
    AUGUSTUS-3.0.2_03774
    FMR1 autosomal homolog 1
    Fragile X messenger ribonucleoprotein 1
    GLEAN_03774

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087400.1 Reference icTriCast1.1 Primary Assembly

      Range
      7274207..7287071
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008193012.3 → XP_008191234.1  RNA-binding protein FXR1 isoform X1

      UniProtKB/TrEMBL
      A0A139WKS1
      Related
      XP_008191234.1, XM_008193012.3
      Conserved Domains (2) summary
      pfam00013
      Location:328 → 398
      KH_1; KH domain
      pfam12235
      Location:401 → 449
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal

    2. XM_008193013.3 → XP_008191235.1  RNA-binding protein FXR1 isoform X3

      UniProtKB/TrEMBL
      A0A139WKS1
      Related
      XP_008191235.1, XM_008193013.3
      Conserved Domains (2) summary
      pfam00013
      Location:328 → 398
      KH_1; KH domain
      pfam12235
      Location:401 → 449
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal

    3. XM_008193014.3 → XP_008191236.1  RNA-binding protein FXR1 isoform X4

      UniProtKB/TrEMBL
      A0A139WKS1
      Related
      XP_008191236.1, XM_008193014.3
      Conserved Domains (2) summary
      pfam00013
      Location:328 → 398
      KH_1; KH domain
      pfam12235
      Location:401 → 503
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal

    4. XM_008193016.3 → XP_008191238.1  RNA-binding protein FXR1 isoform X5

      UniProtKB/TrEMBL
      A0A139WKS1
      Related
      XP_008191238.1, XM_008193016.3
      Conserved Domains (2) summary
      pfam00013
      Location:328 → 398
      KH_1; KH domain
      pfam12235
      Location:401 → 501
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal

    5. XM_964303.5 → XP_969396.3  RNA-binding protein FXR1 isoform X2

      UniProtKB/TrEMBL
      A0A139WKS1
      Related
      XP_969396.3, XM_964303.5
      Conserved Domains (2) summary
      pfam00013
      Location:311 → 381
      KH_1; KH domain
      pfam12235
      Location:384 → 432
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal

    6. XM_008193017.3 → XP_008191239.1  fragile X messenger ribonucleoprotein 1 homolog isoform X6

      UniProtKB/TrEMBL
      A0A139WKS1
      Related
      XP_008191239.1, XM_008193017.3
      Conserved Domains (2) summary
      pfam00013
      Location:311 → 381
      KH_1; KH domain
      pfam12235
      Location:384 → 484
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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