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    Prx4 Peroxiredoxin 4 [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 664161, updated on 12-Apr-2024

    Summary

    Gene symbol
    Prx4
    Gene description
    Peroxiredoxin 4
    Locus tag
    TcasGA2_TC001071
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
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    Genomic context

    See Prx4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 4 NC_087397.1 (4719845..4721029, complement)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG2 NC_007417.3 (10502458..10503512)

    Chromosome 4 - NC_087397.1Genomic Context describing neighboring genes Neighboring gene putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 Neighboring gene Chaperonin containing TCP1 subunit 8 Neighboring gene Pendulin Neighboring gene shattered Neighboring gene Chromatin assembly factor 1, p105 subunit Neighboring gene uncharacterized protein Neighboring gene dissatisfaction

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in hydrogen peroxide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    peroxiredoxin-2
    Names
    AUGUSTUS-3.0.2_01071
    GLEAN_01071
    Peroxiredoxin 1-like Protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087397.1 Reference icTriCast1.1 Primary Assembly

      Range
      4719845..4721029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_970175.5XP_975268.1  peroxiredoxin-2

      See identical proteins and their annotated locations for XP_975268.1

      UniProtKB/TrEMBL
      D6W9X8
      Conserved Domains (2) summary
      COG0450
      Location:53243
      AhpC; Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin) [Defense mechanisms]
      cd03015
      Location:54225
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...