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    uif sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein uif [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 663838, updated on 2-Apr-2025
    Gene symbol
    uif
    Gene description
    sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein uif
    Locus tag
    TcasGA2_TC000871
    See related
    EnsemblRapid:GeneID_663838
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Also known as
    SP1070
    Orthologs
    fruit fly all
    NEW
    Try the new Gene table
    Try the new Transcript table
    See uif in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 4 NC_087397.1 (7672705..7697190, complement)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG2 NC_007417.3 (7540803..7565325)

    Chromosome 4 - NC_087397.1Genomic Context describing neighboring genes Neighboring gene draper Neighboring gene UPF3 regulator of nonsense mediated mRNA decay Neighboring gene serine protease nudel Neighboring gene zinc finger protein elbow B

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Notch binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    uncharacterized protein uif
    Names
    AUGUSTUS-3.0.2_00871
    GLEAN_00871
    uninflatable

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087397.1 Reference icTriCast1.1 Primary Assembly

      Range
      7672705..7697190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008203190.3 → XP_008201412.1  uncharacterized protein uif isoform X2

      Related
      XP_008201412.1, XM_008203190.3
      Conserved Domains (15) summary
      cd00033
      Location:1049 → 1104
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00034
      Location:32 → 164
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
      smart00179
      Location:789 → 826
      EGF_CA; Calcium-binding EGF-like domain
      smart00231
      Location:825 → 975
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      PHA02927
      Location:1044 → 1290
      PHA02927; secreted complement-binding protein; Provisional
      cd00041
      Location:323 → 433
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00054
      Location:2057 → 2093
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00057
      Location:830 → 974
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00112
      Location:169 → 203
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:2023 → 2053
      EGF; EGF-like domain
      pfam00084
      Location:611 → 667
      Sushi; Sushi repeat (SCR repeat)
      pfam07699
      Location:3278 → 3325
      GCC2_GCC3; GCC2 and GCC3
      pfam14670
      Location:986 → 1014
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl03620
      Location:2795 → 2875
      DUF5011; Domain of unknown function (DUF5011)
      cl22861
      Location:2586 → 2738
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

    2. XM_008203189.3 → XP_008201411.1  uncharacterized protein uif isoform X1

      UniProtKB/TrEMBL
      D6W8V9
      Related
      XP_008201411.1, XM_008203189.3
      Conserved Domains (15) summary
      cd00033
      Location:1049 → 1104
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00034
      Location:32 → 164
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
      smart00179
      Location:789 → 826
      EGF_CA; Calcium-binding EGF-like domain
      smart00231
      Location:825 → 975
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      PHA02927
      Location:1044 → 1290
      PHA02927; secreted complement-binding protein; Provisional
      cd00041
      Location:323 → 433
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00054
      Location:2057 → 2093
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00057
      Location:830 → 974
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00112
      Location:169 → 203
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:2023 → 2053
      EGF; EGF-like domain
      pfam00084
      Location:611 → 667
      Sushi; Sushi repeat (SCR repeat)
      pfam07699
      Location:3301 → 3348
      GCC2_GCC3; GCC2 and GCC3
      pfam14670
      Location:986 → 1014
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl03620
      Location:2795 → 2875
      DUF5011; Domain of unknown function (DUF5011)
      cl22861
      Location:2586 → 2738
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

    3. XM_015985070.2 → XP_015840556.1  uncharacterized protein uif isoform X1

      UniProtKB/TrEMBL
      D6W8V9
      Related
      XP_015840556.1, XM_015985070.2
      Conserved Domains (15) summary
      cd00033
      Location:1049 → 1104
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00034
      Location:32 → 164
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
      smart00179
      Location:789 → 826
      EGF_CA; Calcium-binding EGF-like domain
      smart00231
      Location:825 → 975
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      PHA02927
      Location:1044 → 1290
      PHA02927; secreted complement-binding protein; Provisional
      cd00041
      Location:323 → 433
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00054
      Location:2057 → 2093
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00057
      Location:830 → 974
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00112
      Location:169 → 203
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:2023 → 2053
      EGF; EGF-like domain
      pfam00084
      Location:611 → 667
      Sushi; Sushi repeat (SCR repeat)
      pfam07699
      Location:3301 → 3348
      GCC2_GCC3; GCC2 and GCC3
      pfam14670
      Location:986 → 1014
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl03620
      Location:2795 → 2875
      DUF5011; Domain of unknown function (DUF5011)
      cl22861
      Location:2586 → 2738
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

    4. XM_015985069.2 → XP_015840555.1  uncharacterized protein uif isoform X1

      UniProtKB/TrEMBL
      D6W8V9
      Related
      XP_015840555.1, XM_015985069.2
      Conserved Domains (15) summary
      cd00033
      Location:1049 → 1104
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00034
      Location:32 → 164
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
      smart00179
      Location:789 → 826
      EGF_CA; Calcium-binding EGF-like domain
      smart00231
      Location:825 → 975
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      PHA02927
      Location:1044 → 1290
      PHA02927; secreted complement-binding protein; Provisional
      cd00041
      Location:323 → 433
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00054
      Location:2057 → 2093
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00057
      Location:830 → 974
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00112
      Location:169 → 203
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:2023 → 2053
      EGF; EGF-like domain
      pfam00084
      Location:611 → 667
      Sushi; Sushi repeat (SCR repeat)
      pfam07699
      Location:3301 → 3348
      GCC2_GCC3; GCC2 and GCC3
      pfam14670
      Location:986 → 1014
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl03620
      Location:2795 → 2875
      DUF5011; Domain of unknown function (DUF5011)
      cl22861
      Location:2586 → 2738
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    Nucleotide Protein Strain
    Heading Accession and Version

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