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    polI DNA polymerase I [ Streptococcus mutans UA159 ]

    Gene ID: 1029369, updated on 20-Aug-2016

    Summary

    Gene symbol
    polI
    Gene description
    DNA polymerase I
    Locus tag
    SMU_297
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Streptococcus mutans UA159 (strain: UA159)
    Lineage
    Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
    Old locus tag
    SMU.297

    Genomic context

    Sequence:
    NC_004350.2 (284102..286738)

    NC_004350.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene bacteriocin peptide

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Base excision repair, organism-specific biosystem (from KEGG)
      Base excision repair, organism-specific biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
    • Base excision repair, conserved biosystem (from KEGG)
      Base excision repair, conserved biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
    • DNA replication, organism-specific biosystem (from KEGG)
      DNA replication, organism-specific biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
    • DNA replication, conserved biosystem (from KEGG)
      DNA replication, conserved biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
    • Homologous recombination, organism-specific biosystem (from KEGG)
      Homologous recombination, organism-specific biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
    • Homologous recombination, conserved biosystem (from KEGG)
      Homologous recombination, conserved biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
    • Metabolic pathways, organism-specific biosystem (from KEGG)
      Metabolic pathways, organism-specific biosystem
      Metabolic pathways
    • Nucleotide excision repair, organism-specific biosystem (from KEGG)
      Nucleotide excision repair, organism-specific biosystemNucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the ...
    • Nucleotide excision repair, conserved biosystem (from KEGG)
      Nucleotide excision repair, conserved biosystemNucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the ...
    • Purine metabolism, organism-specific biosystem (from KEGG)
      Purine metabolism, organism-specific biosystem
      Purine metabolism
    • Purine metabolism, conserved biosystem (from KEGG)
      Purine metabolism, conserved biosystem
      Purine metabolism
    • Pyrimidine metabolism, organism-specific biosystem (from KEGG)
      Pyrimidine metabolism, organism-specific biosystem
      Pyrimidine metabolism
    • Pyrimidine metabolism, conserved biosystem (from KEGG)
      Pyrimidine metabolism, conserved biosystem
      Pyrimidine metabolism

    General protein information

    Names
    DNA polymerase I
    NP_720755.1
    • Best Blastp Hit: sp|P13252|DPO1_STRPN DNA POLYMERASE I (POL I) >gi|98023|pir||A32949 DNA-directed DNA polymerase (EC 2.7.7.7) - Streptococcus pneumoniae >gi|153765|gb|AAA26954.1| (J04479) DNA polymerase I [Streptococcus pneumoniae]

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004350.2 Reference assembly

      Range
      284102..286738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_720755.1 DNA polymerase I [Streptococcus mutans UA159]

      See identical proteins and their annotated locations for NP_720755.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q8DVZ5
      Conserved Domains (5) summary
      cd08637
      Location:497875
      DNA_pol_A_pol_I_C; Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication
      cd06140
      Location:315487
      DNA_polA_I_Bacillus_like_exo; inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases
      cd09859
      Location:7174
      PIN_53EXO; PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs
      PRK05755
      Location:4878
      PRK05755; DNA polymerase I; Provisional
      pfam01367
      Location:179270
      5_3_exonuc; 5'-3' exonuclease, C-terminal SAM fold
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