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    pbp2a membrane carboxypeptidase, penicillin-binding protein 2a [ Streptococcus mutans UA159 ]

    Gene ID: 1029145, updated on 13-Aug-2016

    Summary

    Gene symbol
    pbp2a
    Gene description
    membrane carboxypeptidase, penicillin-binding protein 2a
    Locus tag
    SMU_1949
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Streptococcus mutans UA159 (strain: UA159)
    Lineage
    Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
    Old locus tag
    SMU.1949

    Genomic context

    Sequence:
    NC_004350.2 (1827651..1829843, complement)

    NC_004350.2Genomic Context describing neighboring genes Neighboring gene transcription antitermination protein NusG Neighboring gene preprotein translocase subunit SecE Neighboring gene pseudouridylate synthase Neighboring gene hypothetical protein

    Pathways from BioSystems

    • Peptidoglycan biosynthesis, organism-specific biosystem (from KEGG)
      Peptidoglycan biosynthesis, organism-specific biosystemPeptidoglycan is a macromolecule made of long aminosugar strands cross-linked by short peptides. It forms the cell wall in bacteria surrounding the cytoplasmic membrane. The glycan strands are typica...
    • Peptidoglycan biosynthesis, conserved biosystem (from KEGG)
      Peptidoglycan biosynthesis, conserved biosystemPeptidoglycan is a macromolecule made of long aminosugar strands cross-linked by short peptides. It forms the cell wall in bacteria surrounding the cytoplasmic membrane. The glycan strands are typica...
    • beta-Lactam resistance, organism-specific biosystem (from KEGG)
      beta-Lactam resistance, organism-specific biosystemThe beta-lactam antibiotics are the most widely used group of antibiotics, which exert their effect by interfering with the structural crosslinking of peptidoglycans in bacterial cell walls. Over the...
    • beta-Lactam resistance, conserved biosystem (from KEGG)
      beta-Lactam resistance, conserved biosystemThe beta-lactam antibiotics are the most widely used group of antibiotics, which exert their effect by interfering with the structural crosslinking of peptidoglycans in bacterial cell walls. Over the...

    General protein information

    Names
    membrane carboxypeptidase, penicillin-binding protein 2a
    NP_722252.1
    • Best Blastp Hit: gb|AAF04735.1|AF101780_1 (AF101780) penicillin-binding protein 2a [Streptococcus pneumoniae]

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004350.2 Reference assembly

      Range
      1827651..1829843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_722252.1 membrane carboxypeptidase, penicillin-binding protein 2a [Streptococcus mutans UA159]

      See identical proteins and their annotated locations for NP_722252.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q8DS80
      Conserved Domains (3) summary
      COG0744
      Location:45660
      MrcB; Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis]
      pfam00912
      Location:98270
      Transgly; Transglycosylase
      cl21491
      Location:368613
      Transpeptidase; Penicillin binding protein transpeptidase domain
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