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    Rgcc regulator of cell cycle [ Mus musculus (house mouse) ]

    Gene ID: 66214, updated on 24-Sep-2017
    Official Symbol
    Rgccprovided by MGI
    Official Full Name
    regulator of cell cycleprovided by MGI
    Primary source
    MGI:MGI:1913464
    See related
    Ensembl:ENSMUSG00000022018 Vega:OTTMUSG00000042059
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rgc32; Rgc-32; 1190002H23Rik
    Orthologs
    Location:
    14; 14 D3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (79288750..79301635, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (79688557..79701442, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene von Willebrand factor A domain containing 8 Neighboring gene predicted gene 4632 Neighboring gene zinc finger protein 957 Neighboring gene predicted gene, 46472 Neighboring gene N(alpha)-acetyltransferase 16, NatA auxiliary subunit

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    R-SMAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein kinase activator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    complement activation ISO
    Inferred from Sequence Orthology
    more info
     
    fibroblast activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cell cycle arrest ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of blood vessel endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell-cell adhesion mediated by cadherin ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cytokine secretion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of fibroblast growth factor production ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitotic cell cycle phase transition ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell cycle arrest ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of collagen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytokine secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of endothelial cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of extracellular matrix assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of extracellular matrix constituent secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mitotic nuclear division ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of sequence-specific DNA binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    regulator of cell cycle RGCC
    Names
    response gene to complement 32 protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025427.2NP_079703.2  regulator of cell cycle RGCC

      See identical proteins and their annotated locations for NP_079703.2

      Status: VALIDATED

      Source sequence(s)
      BC049580, BY083770, CK792184
      Consensus CDS
      CCDS49552.1
      UniProtKB/Swiss-Prot
      Q9DBX1
      Related
      ENSMUSP00000022595.7, OTTMUSP00000061506, ENSMUST00000022595.7, OTTMUST00000110301
      Conserved Domains (1) summary
      pfam15151
      Location:27137
      RGCC; Response gene to complement 32 protein family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      79288750..79301635 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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