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    Myef2 myelin expression factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679712, updated on 8-Oct-2017
    Official Symbol
    Myef2provided by RGD
    Official Full Name
    myelin expression factor 2provided by RGD
    Primary source
    RGD:1306547
    See related
    Ensembl:ENSRNOG00000005258
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Orthologs
    Location:
    3q36
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (117353490..117389582, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (123877348..123913393, complement)

    Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350454 Neighboring gene uncharacterized LOC108350455 Neighboring gene solute carrier family 24 member 5 Neighboring gene uncharacterized LOC103691879 Neighboring gene cortexin 2 Neighboring gene solute carrier family 12 member 1 Neighboring gene uncharacterized LOC102555270

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC109392

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    myotube differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    myelin expression factor 2
    Names
    myelin basic protein expression factor 2, repressor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013205.2NP_001013223.2  myelin expression factor 2

      Status: INFERRED

      Source sequence(s)
      AABR07053633, AABR07053634, AABR07072920
      UniProtKB/TrEMBL
      D4AEI5
      Related
      ENSRNOP00000007103.5, ENSRNOT00000007103.6
      Conserved Domains (4) summary
      TIGR01628
      Location:115587
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12386
      Location:226299
      RRM2_hnRNPM_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein M (hnRNP M) and similar proteins
      cd12658
      Location:92167
      RRM1_MYEF2; RNA recognition motif 1 in vertebrate myelin expression factor 2 (MEF-2)
      cd12662
      Location:515591
      RRM3_MYEF2; RNA recognition motif 3 in vertebrate myelin expression factor 2 (MEF-2)

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

      Range
      117353490..117389582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234932.2XP_006234994.1  myelin expression factor 2 isoform X3

      Conserved Domains (4) summary
      TIGR01628
      Location:115546
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12386
      Location:226299
      RRM2_hnRNPM_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein M (hnRNP M) and similar proteins
      cd12658
      Location:92167
      RRM1_MYEF2; RNA recognition motif 1 in vertebrate myelin expression factor 2 (MEF-2)
      cd12662
      Location:474550
      RRM3_MYEF2; RNA recognition motif 3 in vertebrate myelin expression factor 2 (MEF-2)
    2. XM_006234930.1XP_006234992.1  myelin expression factor 2 isoform X1

      Conserved Domains (4) summary
      TIGR01628
      Location:115570
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12386
      Location:226299
      RRM2_hnRNPM_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein M (hnRNP M) and similar proteins
      cd12658
      Location:92167
      RRM1_MYEF2; RNA recognition motif 1 in vertebrate myelin expression factor 2 (MEF-2)
      cd12662
      Location:498574
      RRM3_MYEF2; RNA recognition motif 3 in vertebrate myelin expression factor 2 (MEF-2)
    3. XM_006234931.2XP_006234993.1  myelin expression factor 2 isoform X2

      Conserved Domains (4) summary
      TIGR01628
      Location:115563
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12386
      Location:226299
      RRM2_hnRNPM_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein M (hnRNP M) and similar proteins
      cd12658
      Location:92167
      RRM1_MYEF2; RNA recognition motif 1 in vertebrate myelin expression factor 2 (MEF-2)
      cd12662
      Location:491567
      RRM3_MYEF2; RNA recognition motif 3 in vertebrate myelin expression factor 2 (MEF-2)

    Alternate Rn_Celera

    Genomic

    1. AC_000071.1 Alternate Rn_Celera

      Range
      111196494..111225673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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