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    LOC102224322 mothers against decapentaplegic homolog 2 [ Xiphophorus maculatus (southern platyfish) ]

    Gene ID: 102224322, updated on 22-Oct-2023

    Summary

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    Gene symbol
    LOC102224322
    Gene description
    mothers against decapentaplegic homolog 2
    See related
    Ensembl:ENSXMAG00000004505
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xiphophorus maculatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
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    Genomic context

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    See LOC102224322 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    102 current X_maculatus-5.0-male (GCF_002775205.1) 11 NC_036453.1 (2916404..2928431)
    101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372251.1 (664718..672065, complement)

    Chromosome 11 - NC_036453.1Genomic Context describing neighboring genes Neighboring gene ring finger and CHY zinc finger domain containing 1 Neighboring gene low-density lipoprotein receptor related-protein 13 Neighboring gene immediate early response 3-interacting protein 1 Neighboring gene uncharacterized LOC111609988 Neighboring gene uncharacterized LOC111609989

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference X_maculatus-5.0-male Primary Assembly

    Genomic

    1. NC_036453.1 Reference X_maculatus-5.0-male Primary Assembly

      Range
      2916404..2928431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023342679.1 → XP_023198447.1  mothers against decapentaplegic homolog 2 isoform X2

      UniProtKB/TrEMBL
      M3ZJJ4
      Conserved Domains (2) summary
      cd10985
      Location:262 → 452
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:8 → 172
      MH1; N-terminal Mad Homology 1 (MH1) domain

    2. XM_023342676.1 → XP_023198444.1  mothers against decapentaplegic homolog 2 isoform X1

      UniProtKB/TrEMBL
      M3ZJJ4, M3ZQL7
      Related
      ENSXMAP00000004510.2, ENSXMAT00000004515.2
      Conserved Domains (2) summary
      cd10985
      Location:266 → 456
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:8 → 172
      MH1; N-terminal Mad Homology 1 (MH1) domain

    3. XM_023342677.1 → XP_023198445.1  mothers against decapentaplegic homolog 2 isoform X1

      UniProtKB/TrEMBL
      M3ZJJ4, M3ZQL7
      Conserved Domains (2) summary
      cd10985
      Location:266 → 456
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:8 → 172
      MH1; N-terminal Mad Homology 1 (MH1) domain

    4. XM_023342678.1 → XP_023198446.1  mothers against decapentaplegic homolog 2 isoform X1

      UniProtKB/TrEMBL
      M3ZJJ4, M3ZQL7
      Conserved Domains (2) summary
      cd10985
      Location:266 → 456
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:8 → 172
      MH1; N-terminal Mad Homology 1 (MH1) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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