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    hnf1a HNF1 homeobox a [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 101167427, updated on 10-Feb-2026
    Gene symbol
    hnf1a
    Gene description
    HNF1 homeobox a
    See related
    EnsemblRapid:ENSORLG00000018971
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See hnf1a in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2026_01 current Olatipes_Hd-rR_3.1 (GCF_053564925.1) 9 NC_136245.1 (13386992..13395262, complement)
    103 previous assembly ASM223467v1 (GCF_002234675.1) 9 NC_019867.2 (21455941..21464186)

    Chromosome 9 - NC_136245.1Genomic Context describing neighboring genes Neighboring gene unc-119 lipid binding chaperone B Neighboring gene uncharacterized LOC111947919 Neighboring gene chromosome 9 C12orf43 homolog Neighboring gene uncharacterized LOC144994555 Neighboring gene musashi RNA binding protein 1b Neighboring gene uncharacterized LOC144994556

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in liver development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pancreas development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    hepatocyte nuclear factor 1-alpha

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_053564925.1-RS_2026_01

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Olatipes_Hd-rR_3.1

    Genomic

    1. NC_136245.1 Reference Olatipes_Hd-rR_3.1

      Range
      13386992..13395262 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023958663.2 → XP_023814431.1  hepatocyte nuclear factor 1-alpha

      UniProtKB/TrEMBL
      A0A3P9HYN6
      Related
      ENSORLP00000023669.2
      Conserved Domains (3) summary
      cd00086
      Location:189 → 262
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam04812
      Location:271 → 488
      HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
      pfam04814
      Location:20 → 158
      HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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