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    six3b SIX homeobox 3b [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 100049355, updated on 5-Sep-2025
    Gene symbol
    six3b
    Gene description
    SIX homeobox 3b
    See related
    EnsemblRapid:ENSORLG00000010313
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Also known as
    six3
    Orthologs
    zebrafish all
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    See six3b in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 19 NC_019877.2 (12581957..12583907)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 19 NC_019877.1 (11464830..11466780)

    Chromosome 19 - NC_019877.2Genomic Context describing neighboring genes Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Neighboring gene uncharacterized LOC105356569 Neighboring gene protein kinase C, epsilon a Neighboring gene endothelial PAS domain protein 1a

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in eye development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    homeobox protein SIX3
    Names
    sine oculis homeobox homolog 3

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104760.1 → NP_001098230.1  homeobox protein SIX3

      See identical proteins and their annotated locations for NP_001098230.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ000937
      UniProtKB/Swiss-Prot
      O73916
      UniProtKB/TrEMBL
      A0A3P9ITS6, H2M3C2
      Related
      ENSORLP00000012924.3, ENSORLT00000012925.3
      Conserved Domains (2) summary
      cd00086
      Location:171 → 219
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam16878
      Location:50 → 163
      SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019877.2 Reference ASM223467v1 Primary Assembly

      Range
      12581957..12583907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O73916.1 GenPept UniProtKB/Swiss-Prot:O73916

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials