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    tlx2 T cell leukemia homeobox 2 [ Gasterosteus aculeatus (three-spined stickleback) ]

    Gene ID: 120817009, updated on 31-Dec-2025
    Gene symbol
    tlx2
    Gene description
    T cell leukemia homeobox 2
    See related
    Ensembl:ENSGACG00000016709
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gasterosteus aculeatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae; Gasterosteus
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See tlx2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2025_12 current fGasAcu3.hap1.1 (GCF_964276395.1) 4 NC_135691.1 (3294759..3305172, complement)
    100 previous assembly GAculeatus_UGA_version5 (GCF_016920845.1) 4 NC_053215.1 (3232765..3242478, complement)

    Chromosome 4 - NC_135691.1Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 24 Neighboring gene nucleophosmin 1b Neighboring gene adenosine deaminase domain containing 1 (testis-specific) Neighboring gene interleukin-2-like protein Neighboring gene interleukin 2

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    T-cell leukemia homeobox protein 2

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_964276395.1-RS_2025_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fGasAcu3.hap1.1

    Genomic

    1. NC_135691.1 Reference fGasAcu3.hap1.1

      Range
      3294759..3305172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_078101927.1 → XP_077958053.1  T-cell leukemia homeobox protein 2 isoform X2

    2. XM_078101930.1 → XP_077958056.1  T-cell leukemia homeobox protein 2 isoform X4

    3. XM_078101938.1 → XP_077958064.1  T-cell leukemia homeobox protein 2 isoform X9

    4. XM_078101932.1 → XP_077958058.1  T-cell leukemia homeobox protein 2 isoform X5

    5. XM_078101935.1 → XP_077958061.1  T-cell leukemia homeobox protein 2 isoform X7

    6. XM_078101933.1 → XP_077958059.1  T-cell leukemia homeobox protein 2 isoform X5

    7. XM_078101931.1 → XP_077958057.1  T-cell leukemia homeobox protein 2 isoform X4

    8. XM_078101924.1 → XP_077958050.1  T-cell leukemia homeobox protein 2 isoform X1

    9. XM_078101928.1 → XP_077958054.1  T-cell leukemia homeobox protein 2 isoform X3

    10. XM_078101936.1 → XP_077958062.1  T-cell leukemia homeobox protein 2 isoform X8

    11. XM_078101934.1 → XP_077958060.1  T-cell leukemia homeobox protein 2 isoform X6

    12. XM_078101929.1 → XP_077958055.1  T-cell leukemia homeobox protein 2 isoform X3

    13. XM_078101925.1 → XP_077958051.1  T-cell leukemia homeobox protein 2 isoform X1

    Nucleotide Protein
    Heading Accession and Version

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