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    Epas1 endothelial PAS domain protein 1 [ Dipodomys ordii (Ord's kangaroo rat) ]

    Gene ID: 105986858, updated on 13-Mar-2024
    Gene symbol
    Epas1
    Gene description
    endothelial PAS domain protein 1
    See related
    Ensembl:ENSDORG00000003635
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Dipodomys ordii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae; Dipodomyinae; Dipodomys
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See Epas1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current Dord_2.0 (GCF_000151885.1) Unplaced Scaffold NW_012267253.1 (6951908..7041553)

    NW_012267253.1Genomic Context describing neighboring genes Neighboring gene cytochrome c, somatic pseudogene Neighboring gene S1 RNA binding domain 1 Neighboring gene protein kinase C epsilon Neighboring gene ATPase H+ transporting V1 subunit E2 Neighboring gene transmembrane protein 247

    Genomic Sequence:
    NW_012267253.1 Unplaced Scaffold Reference Dord_2.0

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    endothelial PAS domain-containing protein 1

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Dipodomys ordii Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Dord_2.0

    Genomic

    1. NW_012267253.1 Reference Dord_2.0

      Range
      6951908..7041553
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013017968.1 → XP_012873422.1  endothelial PAS domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A1S3FBU0
      Related
      ENSDORP00000024197.1, ENSDORT00000036298.1
      Conserved Domains (7) summary
      smart00091
      Location:86 → 147
      PAS; PAS domain
      cd00083
      Location:12 → 68
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cd00130
      Location:241 → 340
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
      pfam05454
      Location:703 → 821
      DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
      pfam08447
      Location:254 → 341
      PAS_3; PAS fold
      pfam08778
      Location:840 → 876
      HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
      pfam11413
      Location:517 → 549
      HIF-1; Hypoxia-inducible factor-1

    2. XM_013017967.1 → XP_012873421.1  endothelial PAS domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1S3FA44
      Conserved Domains (7) summary
      smart00091
      Location:93 → 154
      PAS; PAS domain
      cd00083
      Location:19 → 75
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cd00130
      Location:248 → 347
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
      pfam05454
      Location:710 → 828
      DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
      pfam08447
      Location:261 → 348
      PAS_3; PAS fold
      pfam08778
      Location:847 → 883
      HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
      pfam11413
      Location:524 → 556
      HIF-1; Hypoxia-inducible factor-1
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases