dbpa D site albumin promoter binding protein a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dbpaprovided by ZNC
Official Full Name: D site albumin promoter binding protein aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060503-802
See related: Ensembl:ENSDARG00000063014 AllianceGenome:ZFIN:ZDB-GENE-060503-802
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dbp1; si:dkey-109n11.1
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in epiphysis; forebrain; and retina. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human DBP (D-box binding PAR bZIP transcription factor). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	19	NC_133194.1 (11273166..11290589, complement)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (10178189..10195553, complement)

Chromosome 19 - NC_133194.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: D site albumin promoter binding protein a

Names: D site of albumin promoter (albumin D-box) binding protein 1; D site of albumin promoter (albumin D-box) binding protein a; D-box binding protein 1; zdbp1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001197060.1 → NP_001183989.1 D site albumin promoter binding protein a

See identical proteins and their annotated locations for NP_001183989.1

Status: PROVISIONAL

Source sequence(s)

GU434296

UniProtKB/TrEMBL

E2E3F3

Related

ENSDARP00000086140.4, ENSDART00000091707.5

Conserved Domains (1) summary

cd14695
Location:295 → 354

bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain