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    mlxip MLX interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 798052, updated on 23-Jun-2024

    Summary

    Official Symbol
    mlxipprovided by ZNC
    Official Full Name
    MLX interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-8
    See related
    Ensembl:ENSDARG00000059474 AllianceGenome:ZFIN:ZDB-GENE-060526-8
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    chrebp; mondoa; wu:fb38e04; si:ch211-110p13.4
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MLXIP (MLX interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See mlxip in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (67314289..67349984, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (66641168..66671249, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:ch211-110p13.9 Neighboring gene uncharacterized LOC101885639 Neighboring gene arginine/serine-rich coiled-coil 2 Neighboring gene uracil DNA glycosylase a Neighboring gene SEBOX homeobox

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001317759.2NP_001304688.1  MLX-interacting protein

      Status: VALIDATED

      Source sequence(s)
      BX957226
      UniProtKB/TrEMBL
      A0A0R5P9U8, F1Q8E5
      Related
      ENSDARP00000115267.2, ENSDART00000144092.3
      Conserved Domains (1) summary
      cd00083
      Location:647706
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      67314289..67349984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476328.1XP_021332003.1  MLX-interacting protein isoform X1

      UniProtKB/TrEMBL
      A0A8M9PY45
      Conserved Domains (2) summary
      cd00083
      Location:624683
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cl26464
      Location:293614
      Atrophin-1; Atrophin-1 family
    2. XM_021476329.1XP_021332004.1  MLX-interacting protein isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q3S4
      Conserved Domains (2) summary
      cd00083
      Location:271330
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cl26247
      Location:9148
      DNA_pol3_delta2; DNA polymerase III, delta subunit