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    e(spl)/hairy-b transcription factor protein [ Ciona intestinalis (vase tunicate) ]

    Gene ID: 778581, updated on 10-Feb-2026
    Gene symbol
    e(spl)/hairy-b
    Gene description
    transcription factor protein
    See related
    Ensembl:ENSCING00000005021
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ciona intestinalis
    Lineage
    Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
    Try the new Gene page
    Try the new Transcripts and proteins table
    See e(spl)/hairy-b in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2026_01 current ASM1832782v2 (GCF_018327825.1) 3 NC_136095.1 (4137880..4141308)
    104 previous assembly KH (GCF_000224145.3) 3 NC_020168.2 (1097532..1099218, complement)

    Chromosome 3 - NC_136095.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100185602 Neighboring gene MAM domain-containing glycosylphosphatidylinositol anchor protein 2-like Neighboring gene putative sodium-coupled neutral amino acid transporter 6 Neighboring gene uncharacterized LOC144743223 Neighboring gene uncharacterized LOC100176248

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Imai KS, et al. Development, 2004 Aug. PMID 15269171
    2. Genomewide surveys of developmentally relevant genes in Ciona intestinalis. Satou Y, et al. Dev Genes Evol, 2003 Jun. PMID 12736827
    3. An integrated database of the ascidian, Ciona intestinalis: towards functional genomics. Satou Y, et al. Zoolog Sci, 2005 Aug. PMID 16141696
    4. A cDNA resource from the basal chordate Ciona intestinalis. Satou Y, et al. Genesis, 2002 Aug. PMID 12203911
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    transcription factor protein

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078216.1 → NP_001071684.1  transcription factor protein

      See identical proteins and their annotated locations for NP_001071684.1

      Status: PROVISIONAL

      Source sequence(s)
      AB210382
      UniProtKB/TrEMBL
      A0A1W2VP10, F6TXK6, Q4H3P0
      Related
      ENSCINP00000010322, ENSCINT00000010322
      Conserved Domains (2) summary
      cd00083
      Location:22 → 86
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam07527
      Location:101 → 140
      Hairy_orange; Hairy Orange

    RefSeqs of Annotated Genomes: GCF_018327825.1-RS_2026_01

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1832782v2 Primary Assembly

    Genomic

    1. NC_136095.1 Reference ASM1832782v2 Primary Assembly

      Range
      4137880..4141308
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_078626428.1 → XP_078482554.1  transcription factor protein

      UniProtKB/TrEMBL
      F6TXK6
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials