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    NADP-ME4 NADP-malic enzyme 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844314, updated on 15-Feb-2024

    Summary

    Gene symbol
    NADP-ME4
    Gene description
    NADP-malic enzyme 4
    Primary source
    Araport:AT1G79750
    Locus tag
    AT1G79750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana NADP-malic enzyme 4; ATNADP-ME4; F19K16.27; F19K16_27; NADP-malic enzyme 4
    Summary
    The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME4 is localized to chloroplasts. The gene is expressed throughout the whole plant and during embryogenesis and germination. A possible involvement in the fatty acid biosynthesis has been proposed.
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    Genomic context

    See NADP-ME4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    18
    Sequence:
    Chromosome: 1; NC_003070.9 (30007288..30011690, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene ncRNA Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene hAT transposon superfamily Neighboring gene downstream target of AGL15-4 Neighboring gene CASP-like protein (DUF1677)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    NADP-malic enzyme 4
    NP_178093.1
    • NADP-malic enzyme 4 (NADP-ME4); CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NADP-malic enzyme 3 (TAIR:AT5G25880.1); Has 9573 Blast hits to 9553 proteins in 2441 species: Archae - 143; Bacteria - 6332; Metazoa - 610; Fungi - 220; Plants - 473; Viruses - 0; Other Eukaryotes - 1795 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30007288..30011690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106624.5NP_178093.1  NADP-malic enzyme 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178093.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56WI7, Q9CA83, Q9MA03
      UniProtKB/TrEMBL
      A0A178W4H6
      Conserved Domains (1) summary
      PLN03129
      Location:67646
      PLN03129; NADP-dependent malic enzyme; Provisional