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    PDE4DIP phosphodiesterase 4D interacting protein [ Homo sapiens (human) ]

    Gene ID: 9659, updated on 29-Mar-2023

    Summary

    Official Symbol
    PDE4DIPprovided by HGNC
    Official Full Name
    phosphodiesterase 4D interacting proteinprovided by HGNC
    Primary source
    HGNC:HGNC:15580
    See related
    Ensembl:ENSG00000178104 MIM:608117; AllianceGenome:HGNC:15580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MMGL; CMYA2
    Summary
    The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
    Expression
    Biased expression in heart (RPKM 86.3), brain (RPKM 18.4) and 10 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PDE4DIP in Genome Data Viewer
    Location:
    1q21.2
    Exon count:
    56
    Annotation release Status Assembly Chr Location
    RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (148808434..149033016)
    RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (145475230..145700086)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (144851427..145075933, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145111649-145112460 Neighboring gene SEC22 homolog B3, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr1:145085325-145085826 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145075157-145075794 Neighboring gene NANOG hESC enhancer GRCh37_chr1:145058822-145059364 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145047676-145048176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145039786-145040507 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145039063-145039785 Neighboring gene NANOG hESC enhancer GRCh37_chr1:145028802-145029303 Neighboring gene RN7SK pseudogene 88 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145023082-145023696 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145022466-145023081 Neighboring gene uncharacterized LOC112268272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145015143-145015643 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:144994512-144995132 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:144993892-144994511 Neighboring gene NANOG hESC enhancer GRCh37_chr1:144976465-144977040 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:144966957-144967786 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:144961997-144962606 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:144937763-144938539 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:144936334-144936835 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:144932913-144933661 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:144932163-144932912 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:144931414-144932162 Neighboring gene RNA, U2 small nuclear 38, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr1:144891435-144892634 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:144867459-144868658 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:144850469-144850968 Neighboring gene NBPF member 9 Neighboring gene profilin-1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC75440, DKFZp781J054

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables enzyme binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables molecular adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables molecular adaptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in centrosome cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein-containing complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in regulation of Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of Golgi organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in myofibril ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    myomegalin
    Names
    cardiomyopathy-associated protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_027693.2 RefSeqGene

      Range
      41253..229841
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001002810.5NP_001002810.1  myomegalin isoform 4

      See identical proteins and their annotated locations for NP_001002810.1

      Status: REVIEWED

      Source sequence(s)
      AC239802
      Consensus CDS
      CCDS72893.1
      UniProtKB/Swiss-Prot
      Q5VU43
      Related
      ENSP00000358353.4, ENST00000369347.8
      Conserved Domains (2) summary
      pfam07989
      Location:673
      Cnn_1N; Centrosomin N-terminal motif 1
      cl26527
      Location:39135
      ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
    2. NM_001002811.3NP_001002811.2  myomegalin isoform 5

      See identical proteins and their annotated locations for NP_001002811.2

      Status: REVIEWED

      Source sequence(s)
      AC239802
      Consensus CDS
      CCDS72894.1
      UniProtKB/Swiss-Prot
      Q5VU43
      Related
      ENSP00000316434.9, ENST00000313431.13
      Conserved Domains (2) summary
      pfam07776
      Location:474
      zf-AD; Zinc-finger associated domain (zf-AD)
      cl25732
      Location:4031095
      SMC_N; RecF/RecN/SMC N terminal domain
    3. NM_001002812.4NP_001002812.2  myomegalin isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC239802
      Consensus CDS
      CCDS72890.1
      UniProtKB/Swiss-Prot
      Q5VU43
      UniProtKB/TrEMBL
      A0A0A0MRL8
      Related
      ENSP00000358355.3, ENST00000369349.7
      Conserved Domains (3) summary
      TIGR02168
      Location:30679
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam07851
      Location:242337
      TMPIT; TMPIT-like protein
      pfam07989
      Location:673
      Cnn_1N; Centrosomin N-terminal motif 1
    4. NM_001195260.2NP_001182189.1  myomegalin isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC239802, BC025406, BI550399, CB529851, DA766011
      UniProtKB/Swiss-Prot
      Q5VU43
      Conserved Domains (2) summary
      PRK12704
      Location:2113
      PRK12704; phosphodiesterase; Provisional
      pfam07989
      Location:141
      Cnn_1N; Centrosomin N-terminal motif 1
    5. NM_001195261.2NP_001182190.1  myomegalin isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC239802, BC025406, BG776644, CB529851, DA766011
      UniProtKB/Swiss-Prot
      Q5VU43
      UniProtKB/TrEMBL
      A0A087WYE4
      Related
      ENSP00000435920.1, ENST00000534536.5
      Conserved Domains (2) summary
      pfam07989
      Location:1376
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam16046
      Location:53118
      FAM76; FAM76 protein
    6. NM_001198832.4NP_001185761.2  myomegalin isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Consensus CDS
      CCDS72888.1
      UniProtKB/Swiss-Prot
      Q5VU43
      UniProtKB/TrEMBL
      A0A087WVF8
      Related
      ENSP00000479409.1, ENST00000618462.4
      Conserved Domains (8) summary
      COG1196
      Location:4211206
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05456
      Location:20092056
      eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
      pfam06758
      Location:15191580
      DUF1220; Repeat of unknown function (DUF1220)
      pfam07851
      Location:308403
      TMPIT; TMPIT-like protein
      pfam07989
      Location:72139
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam15678
      Location:18231886
      SPICE; Centriole duplication and mitotic chromosome congression
      cl09111
      Location:116233
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    7. NM_001198834.5NP_001185763.3  myomegalin isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Consensus CDS
      CCDS72892.1
      UniProtKB/Swiss-Prot
      Q5VU43
      UniProtKB/TrEMBL
      A0A0A0MRM1
      Related
      ENSP00000358363.4, ENST00000369356.8
      Conserved Domains (7) summary
      TIGR02168
      Location:5679
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05456
      Location:21152162
      eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
      pfam06758
      Location:15631624
      DUF1220; Repeat of unknown function (DUF1220)
      pfam07851
      Location:242337
      TMPIT; TMPIT-like protein
      pfam07989
      Location:673
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam15678
      Location:19291992
      SPICE; Centriole duplication and mitotic chromosome congression
      cl09111
      Location:50167
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    8. NM_001350520.2NP_001337449.1  myomegalin isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Consensus CDS
      CCDS91044.1
      Related
      ENSP00000516056.1, ENST00000704840.1
      Conserved Domains (3) summary
      pfam06758
      Location:17181785
      DUF1220; Repeat of unknown function (DUF1220)
      pfam07776
      Location:474
      zf-AD; Zinc-finger associated domain (zf-AD)
      cl25732
      Location:4031237
      SMC_N; RecF/RecN/SMC N terminal domain
    9. NM_001350521.4NP_001337450.1  myomegalin isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      pfam06758
      Location:16931760
      DUF1220; Repeat of unknown function (DUF1220)
      cl25732
      Location:140816
      SMC_N; RecF/RecN/SMC N terminal domain
    10. NM_001350522.3NP_001337451.1  myomegalin isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      pfam06758
      Location:16221689
      DUF1220; Repeat of unknown function (DUF1220)
      cl25732
      Location:69745
      SMC_N; RecF/RecN/SMC N terminal domain
    11. NM_001350523.3NP_001337452.1  myomegalin isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      pfam06758
      Location:15111578
      DUF1220; Repeat of unknown function (DUF1220)
      cl25732
      Location:69745
      SMC_N; RecF/RecN/SMC N terminal domain
    12. NM_001377392.2NP_001364321.1  myomegalin isoform 14

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Consensus CDS
      CCDS91040.1
      UniProtKB/TrEMBL
      A0A8Q3WM32
      Related
      ENSP00000512174.1, ENST00000695794.1
      Conserved Domains (5) summary
      COG0419
      Location:167767
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:19812203
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:3771175
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06758
      Location:16931760
      DUF1220; Repeat of unknown function (DUF1220)
      pfam07989
      Location:143210
      Cnn_1N; Centrosomin N-terminal motif 1
    13. NM_001377393.2NP_001364322.1  myomegalin isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (5) summary
      COG0419
      Location:96696
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:18002022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:3061104
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06758
      Location:15121579
      DUF1220; Repeat of unknown function (DUF1220)
      pfam07989
      Location:72139
      Cnn_1N; Centrosomin N-terminal motif 1
    14. NM_001395297.1NP_001382226.1  myomegalin isoform 16

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Conserved Domains (2) summary
      COG1196
      Location:20072229
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:4031237
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    15. NM_001395298.1NP_001382227.1  myomegalin isoform 17

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Consensus CDS
      CCDS91041.1
      UniProtKB/TrEMBL
      A0A075B749
      Related
      ENSP00000462316.2, ENST00000585156.5
      Conserved Domains (5) summary
      COG0419
      Location:167767
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:19802202
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:3771175
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06758
      Location:16921759
      DUF1220; Repeat of unknown function (DUF1220)
      pfam07989
      Location:143210
      Cnn_1N; Centrosomin N-terminal motif 1
    16. NM_001395299.1NP_001382228.1  myomegalin isoform 18

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Conserved Domains (2) summary
      COG1196
      Location:19442166
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:4031201
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    17. NM_001395300.1NP_001382229.1  myomegalin isoform 19

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (3) summary
      COG0419
      Location:140730
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:19442166
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:3401138
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    18. NM_001395301.1NP_001382230.1  myomegalin isoform 20

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Conserved Domains (2) summary
      COG1196
      Location:20062175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:4031201
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    19. NM_001395302.1NP_001382231.1  myomegalin isoform 21

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Consensus CDS
      CCDS91042.1
      UniProtKB/TrEMBL
      A0A8Q3SI21
      Related
      ENSP00000512160.1, ENST00000695768.1
      Conserved Domains (3) summary
      COG1196
      Location:19442113
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:150779
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02463
      Location:4951231
      SMC_N; RecF/RecN/SMC N terminal domain
    20. NM_001395303.1NP_001382232.1  myomegalin isoform 22

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18702092
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:140816
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    21. NM_001395304.1NP_001382233.1  myomegalin isoform 23

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18482017
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    22. NM_001395305.1NP_001382234.1  myomegalin isoform 24

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18482017
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    23. NM_001395306.1NP_001382235.1  myomegalin isoform 25

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18002022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    24. NM_001395307.1NP_001382236.1  myomegalin isoform 26

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18702055
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:140816
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    25. NM_001395308.1NP_001382237.1  myomegalin isoform 27

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18472032
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    26. NM_001395309.1NP_001382238.1  myomegalin isoform 28

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Conserved Domains (2) summary
      COG1196
      Location:17832005
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:4031247
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    27. NM_001395310.1NP_001382239.1  myomegalin isoform 29

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18482033
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    28. NM_001395311.1NP_001382240.1  myomegalin isoform 30

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:17381907
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    29. NM_001395312.1NP_001382241.1  myomegalin isoform 31

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:4211336
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    30. NM_001395313.1NP_001382242.1  myomegalin isoform 32

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:18111996
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:79708
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    31. NM_001395314.1NP_001382243.1  myomegalin isoform 33

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Conserved Domains (2) summary
      COG1196
      Location:4211336
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    32. NM_001395315.1NP_001382244.1  myomegalin isoform 34

      Status: REVIEWED

      Source sequence(s)
      AC239802
      Consensus CDS
      CCDS91045.1
      Related
      ENSP00000433392.1, ENST00000529945.2
      Conserved Domains (2) summary
      TIGR02168
      Location:4531095
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam18615
      Location:1376
      SMYLE_N; Short myomegalin-like EB1 binding proteins, N-terminal domain
    33. NM_001395316.1NP_001382245.1  myomegalin isoform 35

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      TIGR02168
      Location:140816
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    34. NM_001395317.1NP_001382246.1  myomegalin isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (2) summary
      PRK02224
      Location:6111088
      PRK02224; DNA double-strand break repair Rad50 ATPase
      TIGR02168
      Location:140816
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    35. NM_001395318.1NP_001382247.1  myomegalin isoform 37

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    36. NM_001395319.1NP_001382248.1  myomegalin isoform 38

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      TIGR02168
      Location:53729
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    37. NM_001395320.1NP_001382249.1  myomegalin isoform 39

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    38. NM_001395321.1NP_001382250.1  myomegalin isoform 40

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      TIGR02168
      Location:79708
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    39. NM_001395322.1NP_001382251.1  myomegalin isoform 41

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      TIGR02168
      Location:18647
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    40. NM_001395323.1NP_001382252.1  myomegalin isoform 42

      Status: REVIEWED

      Source sequence(s)
      AC239802
      Consensus CDS
      CCDS91046.1
      UniProtKB/TrEMBL
      E9PQG4
      Related
      ENSP00000436791.1, ENST00000479408.6
      Conserved Domains (2) summary
      TIGR02168
      Location:151466
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02463
      Location:28724
      SMC_N; RecF/RecN/SMC N terminal domain
    41. NM_001395324.1NP_001382253.1  myomegalin isoform 43

      Status: REVIEWED

      Source sequence(s)
      AC239802
      Conserved Domains (2) summary
      TIGR02168
      Location:151464
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02463
      Location:28722
      SMC_N; RecF/RecN/SMC N terminal domain
    42. NM_001395325.1NP_001382254.1  myomegalin isoform 44

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Related
      ENSP00000512159.1, ENST00000695767.1
      Conserved Domains (1) summary
      COG1196
      Location:140342
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    43. NM_001395326.1NP_001382255.1  myomegalin isoform 45

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Related
      ENSP00000512161.1, ENST00000695769.1
      Conserved Domains (1) summary
      COG1196
      Location:67271
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    44. NM_001395327.1NP_001382256.1  myomegalin isoform 46

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (1) summary
      COG4942
      Location:57234
      EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    45. NM_001395328.1NP_001382257.1  myomegalin isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
    46. NM_001395329.1NP_001382258.1  myomegalin isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Conserved Domains (2) summary
      PRK12704
      Location:2113
      PRK12704; phosphodiesterase; Provisional
      pfam07989
      Location:141
      Cnn_1N; Centrosomin N-terminal motif 1
    47. NM_001395426.1NP_001382355.1  myomegalin isoform 47

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804, AC245389
      Consensus CDS
      CCDS91043.1
      UniProtKB/TrEMBL
      A0A8Q3SI83
      Related
      ENSP00000512175.1, ENST00000695795.1
      Conserved Domains (2) summary
      COG1196
      Location:19102132
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:69745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    48. NM_014644.7NP_055459.5  myomegalin isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC239804
      Consensus CDS
      CCDS72891.1
      UniProtKB/Swiss-Prot
      Q5VU43, Q9HCP5
      UniProtKB/TrEMBL
      A0A0A0MRM0
      Related
      ENSP00000358360.3, ENST00000369354.7
      Conserved Domains (2) summary
      pfam06758
      Location:15561623
      DUF1220; Repeat of unknown function (DUF1220)
      cl25732
      Location:5679
      SMC_N; RecF/RecN/SMC N terminal domain
    49. NM_022359.8NP_071754.3  myomegalin isoform 3

      See identical proteins and their annotated locations for NP_071754.3

      Status: REVIEWED

      Source sequence(s)
      AC239802, AC245389
      Consensus CDS
      CCDS72887.1
      UniProtKB/Swiss-Prot
      Q5VU43
      Related
      ENSP00000482121.1, ENST00000530472.5
      Conserved Domains (2) summary
      pfam07989
      Location:143210
      Cnn_1N; Centrosomin N-terminal motif 1
      cl09111
      Location:187304
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      148808434..149033016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      145475230..145700086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)