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    TTC30A tetratricopeptide repeat domain 30A [ Homo sapiens (human) ]

    Gene ID: 92104, updated on 16-Sep-2018

    Summary

    Official Symbol
    TTC30Aprovided by HGNC
    Official Full Name
    tetratricopeptide repeat domain 30Aprovided by HGNC
    Primary source
    HGNC:HGNC:25853
    See related
    Ensembl:ENSG00000197557 Vega:OTTHUMG00000132528
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IFT70A; TTC30B
    Orthologs

    Genomic context

    See TTC30A in Genome Data Viewer
    Location:
    2q31.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (177614298..177618966, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (178479026..178483694, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene alkylglycerone phosphate synthase Neighboring gene uncharacterized LOC105373762 Neighboring gene tetratricopeptide repeat domain 30B Neighboring gene uncharacterized LOC105373764 Neighboring gene phosphodiesterase 11A Neighboring gene apoptosis inhibitor 5 pseudogene 2

    Genomic regions, transcripts, and products

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Vif vif HIV-1 Vif downregulates the expression of tetratricopeptide repeat domain 30A (TTC30A) in Vif-expression T cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from BioSystems

    • Cilium Assembly, organism-specific biosystem (from REACTOME)
      Cilium Assembly, organism-specific biosystemCilia are membrane covered organelles that extend from the surface of eukaryotic cells. Cilia may be motile, such as respiratory cilia) or non-motile (such as the primary cilium) and are distinguishe...
    • Intraflagellar transport, organism-specific biosystem (from REACTOME)
      Intraflagellar transport, organism-specific biosystemIntraflagellar transport (IFT) is a motor-based process that controls the anterograde and retrograde transport of large protein complexes, ciliary cargo and structural components along the ciliary ax...
    • Organelle biogenesis and maintenance, organism-specific biosystem (from REACTOME)
      Organelle biogenesis and maintenance, organism-specific biosystemThis module describes the biogenesis of organelles. Organelles are subcellular structures of distinctive morphology and function. The organelles of human cells include: mitochondria, endoplasmic reti...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ13946, FLJ77601

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    intraciliary transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intraciliary transport particle B IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    tetratricopeptide repeat protein 30A
    Names
    TPR repeat protein 30A
    TPR repeat protein 30B
    Tetratricopeptide repeat protein 30B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152275.3NP_689488.3  tetratricopeptide repeat protein 30A

      See identical proteins and their annotated locations for NP_689488.3

      Status: VALIDATED

      Source sequence(s)
      AC073834, BC042848, BM684657
      Consensus CDS
      CCDS2276.1
      UniProtKB/Swiss-Prot
      Q86WT1
      Related
      ENSP00000347915.4, OTTHUMP00000163351, ENST00000355689.5, OTTHUMT00000255728
      Conserved Domains (3) summary
      sd00006
      Location:159182
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:159216
      TPR_11; TPR repeat
      pfam13432
      Location:1676
      TPR_16; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

      Range
      177614298..177618966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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