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    FCGBP Fc fragment of IgG binding protein [ Homo sapiens (human) ]

    Gene ID: 8857, updated on 15-Jun-2019

    Summary

    Official Symbol
    FCGBPprovided by HGNC
    Official Full Name
    Fc fragment of IgG binding proteinprovided by HGNC
    Primary source
    HGNC:HGNC:13572
    See related
    MIM:617553
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FC(GAMMA)BP
    Annotation information
    Annotation category: spans an assembly gap
    Annotation category: partial on reference assembly
    Expression
    Biased expression in colon (RPKM 352.9), thyroid (RPKM 129.4) and 4 other tissues See more
    Orthologs

    Genomic context

    See FCGBP in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (39863323..39934626, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (40353963..40440910, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene dual specificity tyrosine phosphorylation regulated kinase 1B Neighboring gene microRNA 6719 Neighboring gene fibrillarin Neighboring gene uncharacterized LOC107987267 Neighboring gene proline rich 13 pseudogene 5 Neighboring gene proteasome 26S subunit, ATPase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular exosome HDA PubMed 

    General protein information

    Preferred Names
    IgGFc-binding protein
    Names
    Human Fc gamma BP
    IgG Fc binding protein
    fcgamma-binding protein antigen
    fcgammaBP

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_003890.2NP_003881.2  IgGFc-binding protein precursor

      See identical proteins and their annotated locations for NP_003881.2

      Status: VALIDATED

      Source sequence(s)
      AC007842, AC011536, BE294466, BM781647, BQ065661, BU731683, BX113070, CD617655, D84239
      UniProtKB/Swiss-Prot
      Q9Y6R7
      Conserved Domains (5) summary
      smart00832
      Location:667742
      C8; This domain contains 8 conserved cysteine residues
      pfam00094
      Location:472627
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:23372390
      TIL; Trypsin Inhibitor like cysteine rich domain
      cl02516
      Location:52355382
      VWD; von Willebrand factor type D domain
      cl17735
      Location:11941245
      VWC; von Willebrand factor type C domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      39863323..39934626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p13 PATCHES

    Genomic

    1. NW_009646206.1 Reference GRCh38.p13 PATCHES

      Range
      123199..209769 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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